Medical Instruments Encyclopedia
Home > Medical Instruments Encyclopedia
Gamma-Glutamyltransferase (GGT) Assay Kit (GCANA Substrate Method)
The Gamma-Glutamyltransferase (GGT) Assay Kit is composed of two main reagents: Reagent 1 contains glycylglycine (165 mmol/L), and Reagent 2 includes γ-L-glutamyl-3-carboxy-4-nitroaniline (GluCANA) (6.6 mmol/L) and sodium azide (1g/L). These components are specifically designed to facilitate the accurate measurement of GGT activity in human serum.
Product English Name:
Gamma-Glutamyltransferase (GGT) Assay Kit (GCANA Substrate Method)
Alias:
GGT Test Kit,Gamma-GT Assay Kit
Intended Use:
This kit is used for the in vitro quantitative determination of gamma-glutamyltransferase (γ-GT) activity in human serum. It is a crucial tool in clinical diagnostics for assessing liver function and detecting liver diseases, biliary obstructions, and other related conditions.
Product Introduction

The Gamma-Glutamyltransferase (GGT) Assay Kit is a specialized diagnostic tool designed to measure the activity of the GGT enzyme in human serum. GGT is an enzyme that plays a significant role in the metabolism of glutathione and the transport of amino acids. Elevated levels of GGT are often associated with liver diseases, making this kit an essential component in clinical diagnostics.

1. The GGT Assay Kit is characterized by its high sensitivity and specificity, ensuring accurate detection of GGT activity. The kit utilizes a colorimetric method, where the substrate GluCANA is hydrolyzed by GGT, producing a colored product that can be measured spectrophotometrically.
2. The kit consists of two reagents: Reagent 1 contains glycylglycine, which acts as an acceptor for the gamma-glutamyl group, and Reagent 2 contains GluCANA, the substrate for GGT, along with sodium azide as a preservative. These components work together to provide a stable and reliable assay environment.
3. The primary use of the GGT Assay Kit is in clinical laboratories for the diagnosis and monitoring of liver diseases. It is also used in research settings to study the role of GGT in various physiological and pathological processes.

The Gamma-Glutamyltransferase (GGT) Assay Kit, also known as the GGT Test Kit, is a vital tool in clinical diagnostics. Its high sensitivity and specificity make it indispensable for detecting liver diseases and other conditions related to GGT activity. The kit's composition, including glycylglycine and GluCANA, ensures accurate and reliable results, making it a trusted choice for healthcare professionals.

Main Features

The GGT Assay Kit offers high sensitivity and specificity for detecting GGT activity, making it a reliable tool for clinical diagnostics and research.

1. The kit employs a colorimetric method, where the hydrolysis of GluCANA by GGT produces a measurable colored product, allowing for precise quantification of enzyme activity.
2. Reagent 1 contains glycylglycine, which facilitates the transfer of the gamma-glutamyl group, enhancing the accuracy of the assay.
3. Reagent 2 includes GluCANA, the substrate for GGT, and sodium azide, which acts as a preservative to maintain the stability of the reagents.
4. The kit is designed for ease of use, with a straightforward protocol that can be easily followed in clinical laboratories.
5. The assay is highly reproducible, providing consistent results across different batches and laboratories.

The GGT Assay Kit stands out for its high sensitivity, specificity, and ease of use. Its colorimetric method ensures accurate detection of GGT activity, while the inclusion of glycylglycine and GluCANA enhances the reliability of the assay. This kit is a valuable tool for both clinical diagnostics and research, offering consistent and reproducible results.

Clinical Applications

The GGT Assay Kit is widely used in clinical settings for the diagnosis and monitoring of liver diseases, biliary obstructions, and other conditions related to GGT activity.

1. In clinical diagnostics, the kit is used to assess liver function and detect liver diseases such as hepatitis, cirrhosis, and liver cancer.
2. The kit is also employed in the diagnosis of biliary obstructions, where elevated GGT levels are a common indicator.
3. In research, the GGT Assay Kit is used to study the role of GGT in various physiological processes, including amino acid transport and glutathione metabolism.
4. The kit is utilized in epidemiological studies to investigate the prevalence of liver diseases in different populations.
5. In toxicology studies, the GGT Assay Kit is used to assess the impact of various toxins on liver function and GGT activity.

The GGT Assay Kit is a versatile tool in both clinical and research settings. Its primary application is in the diagnosis and monitoring of liver diseases, but it also plays a crucial role in research, toxicology, and epidemiology. The kit's ability to accurately measure GGT activity makes it an indispensable resource for healthcare professionals and researchers alike.

Purchasing Guide

When purchasing the GGT Assay Kit, it is important to consider product specifications, types, budget, and intended use to ensure the best fit for your needs.

1. Product parameters: Ensure the kit meets the required sensitivity, specificity, and reproducibility standards for your application.
2. Product types: Choose between different kit formats, such as single-use or bulk packs, depending on your laboratory's needs.
3. Budget: Consider the cost per test and the overall budget for your laboratory when selecting a kit.
4. Usage scenarios: Determine the specific applications for which the kit will be used, such as clinical diagnostics or research, to select the most appropriate product.

Purchasing the GGT Assay Kit requires careful consideration of various factors, including product specifications, types, budget, and intended use. By evaluating these aspects, you can ensure that the kit you choose will meet your laboratory's needs and provide reliable results for your specific applications.

 Precautions

Proper handling and storage of the GGT Assay Kit are essential to ensure accurate results and maintain the integrity of the reagents.

1. Always follow the manufacturer's instructions for storage and handling to prevent degradation of the reagents.
2. Use appropriate protective equipment, such as gloves and lab coats, when handling the reagents to avoid contamination.
3. Ensure that all equipment used in the assay, such as pipettes and spectrophotometers, are properly calibrated and maintained.
4. Avoid exposing the reagents to extreme temperatures or direct sunlight, as this can affect their stability and performance.
5. Dispose of used reagents and materials according to local regulations and laboratory safety protocols.

Handling the GGT Assay Kit with care is crucial for obtaining accurate and reliable results. Proper storage, use of protective equipment, and adherence to safety protocols are essential to maintain the integrity of the reagents and ensure the success of the assay. By following these precautions, you can minimize the risk of contamination and ensure the longevity of the kit.

Easy procurement

We have the latest medical device product database in China, which can quickly meet your procurement needs.

Submit your purchase list, and we will reply to your inquiry within half an hour at the earliest.

Quickly respond to your procurement needs:
Upload your purchase list
Support EXCEL/PDF/Word/compressed files