Medical Instruments Encyclopedia
Home > Medical Instruments Encyclopedia
β-Amyloid 1-42 (Aβ1-42) Assay Kit (Magnetic Particle Chemiluminescence Method)
The kit consists of Reagent R1, Reagent R2, calibrators, and quality controls. Reagent R1 contains magnetic particles coated with Aβ1-42 antibodies (approximately 0.07 mg/mL), PBS buffer (10 mmol/L), and ProClin 300 (0.5 g/L). Reagent R2 includes Aβ1-42-acridinium ester conjugate (3 mg/L), PBS buffer (10 mmol/L), and ProClin 300 (0.5 g/L). Calibrators contain Aβ1-42 antigen, mannitol, and PBS, with levels ranging from 0 pg/mL to 1000 pg/mL. Quality controls also contain Aβ1-42 antigen, mannitol, and PBS, with levels ranging from 31.25 pg/mL to 1000 pg/mL.
Product English Name:
β-Amyloid 1-42 (Aβ1-42) Assay Kit (Magnetic Particle Chemiluminescence Method)
Alias:
Aβ1-42 Detection Kit,Amyloid Beta Assay Kit
Intended Use:
This kit is designed for the quantitative detection of β-amyloid 1-42 levels in human serum and plasma samples in vitro. It is widely used in research and clinical settings to study Alzheimer's disease and other neurodegenerative disorders.
Product Introduction

The β-Amyloid 1-42 (Aβ1-42) Assay Kit utilizes magnetic particle chemiluminescence technology to accurately measure Aβ1-42 levels in biological samples. This kit is essential for researchers and clinicians studying Alzheimer's disease, as Aβ1-42 is a key biomarker in the pathogenesis of the disease. The kit offers high sensitivity, specificity, and reproducibility, making it a reliable tool for both research and diagnostic purposes.

1. The kit features a highly sensitive chemiluminescence detection system, which ensures accurate and reproducible results. The magnetic particle-based assay format enhances the binding efficiency of Aβ1-42 antibodies, leading to improved detection limits.
2. The kit is composed of Reagent R1, which contains magnetic particles coated with Aβ1-42 antibodies, and Reagent R2, which includes an Aβ1-42-acridinium ester conjugate. Calibrators and quality controls are provided to ensure the accuracy and reliability of the assay.
3. This kit is primarily used for the quantitative detection of Aβ1-42 levels in human serum and plasma samples. It is widely applied in research on Alzheimer's disease and other neurodegenerative disorders, as well as in clinical diagnostics.

The β-Amyloid 1-42 (Aβ1-42) Assay Kit is a cutting-edge tool for detecting Aβ1-42 levels in biological samples. Its high sensitivity and specificity make it indispensable for researchers and clinicians studying Alzheimer's disease. The kit's robust design and reliable performance ensure accurate results, making it a trusted choice in both research and clinical settings.

Main Features

The main features of the Aβ1-42 Assay Kit include high sensitivity, specificity, and reproducibility. The kit utilizes magnetic particle chemiluminescence technology, which enhances the accuracy of Aβ1-42 detection in biological samples.

1. High Sensitivity: The chemiluminescence detection system ensures that even low concentrations of Aβ1-42 can be accurately measured, making it ideal for early detection of Alzheimer's disease.
2. Specificity: The kit is designed to specifically detect Aβ1-42, minimizing cross-reactivity with other amyloid proteins, which ensures reliable and accurate results.
3. Reproducibility: The inclusion of calibrators and quality controls ensures that the assay produces consistent results across different runs and laboratories.
4. Magnetic Particle Technology: The use of magnetic particles enhances the binding efficiency of Aβ1-42 antibodies, leading to improved detection limits and assay performance.
5. Wide Application: The kit is suitable for both research and clinical diagnostics, making it a versatile tool for studying Alzheimer's disease and other neurodegenerative disorders.

The Aβ1-42 Assay Kit stands out for its high sensitivity, specificity, and reproducibility. Its advanced magnetic particle chemiluminescence technology ensures accurate detection of Aβ1-42, making it an essential tool for researchers and clinicians. Whether used in research or clinical diagnostics, this kit delivers reliable and consistent results.

Clinical Applications

The Aβ1-42 Assay Kit is widely used in clinical research and diagnostics, particularly in the study of Alzheimer's disease. It provides a reliable method for quantifying Aβ1-42 levels in human serum and plasma samples.

1. Alzheimer's Disease Research: The kit is extensively used in research to study the role of Aβ1-42 in the pathogenesis of Alzheimer's disease, helping to identify potential therapeutic targets.
2. Clinical Diagnostics: In clinical settings, the kit is used to measure Aβ1-42 levels in patients, aiding in the diagnosis and monitoring of Alzheimer's disease.
3. Drug Development: The kit is also used in drug development studies to evaluate the efficacy of new treatments targeting Aβ1-42 in Alzheimer's disease.
4. Biomarker Studies: Researchers use the kit to study Aβ1-42 as a biomarker in various neurodegenerative disorders, providing insights into disease progression and treatment outcomes.
5. Longitudinal Studies: The kit is ideal for longitudinal studies, allowing researchers to track changes in Aβ1-42 levels over time, which is crucial for understanding disease progression.

The Aβ1-42 Assay Kit is a versatile tool in both clinical research and diagnostics. Its ability to accurately quantify Aβ1-42 levels makes it invaluable for studying Alzheimer's disease, developing new treatments, and monitoring patient outcomes. Whether in the lab or the clinic, this kit provides reliable and actionable insights.

Purchasing Guide

When purchasing the Aβ1-42 Assay Kit, it is important to consider product specifications, types, budget, and intended use. This guide provides key considerations to help you make an informed decision.

1. Product Specifications: Ensure that the kit meets your specific requirements, including sensitivity, specificity, and reproducibility. Check the kit's components, such as reagents, calibrators, and quality controls, to ensure they align with your needs.
2. Product Types: The kit is available in different formats, including research-grade and clinical-grade versions. Choose the type that best suits your application, whether for research or clinical diagnostics.
3. Budget: Consider your budget when selecting the kit. While higher-priced kits may offer additional features or higher sensitivity, ensure that the cost aligns with your project's requirements and funding.
4. Intended Use: Determine the primary use of the kit, whether for research, clinical diagnostics, or drug development. This will help you select the most appropriate kit for your specific needs.

Purchasing the Aβ1-42 Assay Kit requires careful consideration of product specifications, types, budget, and intended use. By evaluating these factors, you can select the kit that best meets your needs, ensuring accurate and reliable results for your research or clinical applications.

 Precautions

When using the Aβ1-42 Assay Kit, it is important to follow proper handling and storage procedures to ensure accurate results and maintain the integrity of the reagents.

1. Storage Conditions: Store the kit at the recommended temperature to maintain the stability of the reagents. Avoid exposure to extreme temperatures or direct sunlight.
2. Handling: Handle the reagents with care, using appropriate personal protective equipment (PPE) to avoid contamination. Follow the manufacturer's instructions for proper handling and disposal.
3. Calibration: Regularly calibrate the assay using the provided calibrators to ensure accurate and consistent results. Avoid using expired or improperly stored calibrators.
4. Quality Control: Use the provided quality controls to monitor the performance of the assay. If the controls fall outside the expected range, troubleshoot the assay before proceeding.
5. Cross-Contamination: Avoid cross-contamination between samples by using clean pipette tips and changing gloves between samples. Ensure that all equipment is properly cleaned and maintained.

Proper handling and storage of the Aβ1-42 Assay Kit are crucial for obtaining accurate and reliable results. By following the recommended precautions, you can ensure the integrity of the reagents and maintain the performance of the assay. Always adhere to the manufacturer's guidelines to achieve the best possible outcomes.

Easy procurement

We have the latest medical device product database in China, which can quickly meet your procurement needs.

Submit your purchase list, and we will reply to your inquiry within half an hour at the earliest.

Quickly respond to your procurement needs:
Upload your purchase list
Support EXCEL/PDF/Word/compressed files