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β-Amyloid 1-42 (Aβ1-42) Detection Kit (Chemiluminescence Method)
This product primarily consists of magnetic particle suspension, labeled working solution, assay diluent, quality control materials (included in B and C packaging), and calibrators (included in A and C packaging). The magnetic particle suspension contains Aβ1-42 antibody-coated magnetic particles with a concentration of at least 0.4mg/mL. The labeled working solution includes acridinium ester-labeled Aβ1-42 antibody with a concentration of at least 0.1mg/L. Quality control materials come in two concentration levels, expected to be (10±20) pg/mL and (50±10) pg/mL, with specific concentrations determined by calibration. Calibrators are available in three concentration levels, traceable to EU-certified reference materials (CRMs): ERM-DA482/IFCC.
Product English Name:
β-Amyloid 1-42 (Aβ1-42) Detection Kit (Chemiluminescence Method)
Alias:
Aβ1-42 Assay Kit,Amyloid Beta Detection Kit
Intended Use:
This product is intended for the clinical in vitro quantitative detection of Aβ1-42 levels in human plasma. It is used to assess the concentration of amyloid beta peptides, which are associated with neurodegenerative diseases such as Alzheimer's disease.
Product Introduction

The β-Amyloid 1-42 (Aβ1-42) Detection Kit is a chemiluminescence-based assay designed for the precise measurement of Aβ1-42 levels in human plasma. This kit is essential for research and clinical diagnostics, particularly in the study of Alzheimer's disease and other amyloid-related disorders. The kit includes high-quality components such as magnetic particle suspension, labeled working solution, and calibrators, ensuring accurate and reliable results.

1. The kit features a highly sensitive chemiluminescence detection method, which allows for the precise quantification of Aβ1-42 levels. This method is known for its high specificity and low background noise, making it ideal for clinical applications.
2. The composition of the kit includes magnetic particle suspension, labeled working solution, and calibrators. The magnetic particles are coated with Aβ1-42 antibodies, ensuring specific binding to the target analyte. The labeled working solution contains acridinium ester, which emits light upon reaction, enabling detection.
3. The primary use of this kit is in clinical diagnostics, particularly for the detection of Aβ1-42 levels in plasma. This is crucial for the early diagnosis and monitoring of Alzheimer's disease, as Aβ1-42 is a key biomarker in the disease's pathology.

The β-Amyloid 1-42 Detection Kit is a sophisticated tool for researchers and clinicians alike. Its high sensitivity and specificity make it an invaluable resource in the fight against Alzheimer's disease. The kit's components are meticulously designed to ensure accurate results, providing confidence in both research and clinical settings.

Main Features

The main features of the Aβ1-42 Detection Kit include high sensitivity, specificity, and reliability. It is designed for the accurate quantification of Aβ1-42 levels in human plasma, making it a critical tool in Alzheimer's disease research and diagnostics.

1. High Sensitivity: The chemiluminescence method used in this kit allows for the detection of very low concentrations of Aβ1-42, making it suitable for early-stage disease detection.
2. Specificity: The kit's components are designed to specifically bind to Aβ1-42, minimizing cross-reactivity with other proteins and ensuring accurate results.
3. Reliability: The inclusion of quality control materials and calibrators ensures that the kit provides consistent and reproducible results across different batches and laboratories.
4. Ease of Use: The kit is designed for straightforward operation, with clear instructions and minimal preparation time, making it accessible to both experienced and novice users.
5. Traceability: The calibrators included in the kit are traceable to EU-certified reference materials, ensuring the accuracy and reliability of the results.

The Aβ1-42 Detection Kit stands out for its precision and ease of use. Its high sensitivity and specificity make it a trusted tool in clinical diagnostics, particularly for Alzheimer's disease. The inclusion of quality control materials and traceable calibrators further enhances its reliability, making it a top choice for researchers and clinicians.

Clinical Applications

The Aβ1-42 Detection Kit is widely used in clinical settings for the quantitative detection of Aβ1-42 levels in human plasma. It is particularly valuable in the diagnosis and monitoring of Alzheimer's disease and other amyloid-related disorders.

1. Alzheimer's Disease Diagnosis: The kit is used to measure Aβ1-42 levels in plasma, which is a key biomarker for Alzheimer's disease. Early detection of elevated Aβ1-42 levels can aid in the early diagnosis of the disease.
2. Disease Monitoring: The kit is also used to monitor the progression of Alzheimer's disease by tracking changes in Aβ1-42 levels over time. This can help in assessing the effectiveness of treatments.
3. Research Applications: In research settings, the kit is used to study the role of Aβ1-42 in neurodegenerative diseases. It provides valuable data for understanding the mechanisms underlying these conditions.
4. Clinical Trials: The kit is employed in clinical trials to evaluate the efficacy of new drugs targeting Aβ1-42. Accurate measurement of Aβ1-42 levels is crucial for assessing the impact of these treatments.
5. Quality Control: The kit is used in laboratories to ensure the accuracy and reliability of Aβ1-42 measurements. The inclusion of quality control materials helps maintain high standards in clinical diagnostics.

The Aβ1-42 Detection Kit is a versatile tool in both clinical and research settings. Its ability to accurately measure Aβ1-42 levels makes it indispensable in the diagnosis and monitoring of Alzheimer's disease. The kit's reliability and ease of use further enhance its value, making it a preferred choice for clinicians and researchers alike.

Purchasing Guide

When purchasing the Aβ1-42 Detection Kit, it is important to consider factors such as product specifications, types, budget, and intended use. This guide provides essential information to help you make an informed decision.

1. Product Specifications: Ensure that the kit meets your specific requirements, including sensitivity, specificity, and the range of Aβ1-42 concentrations it can detect. Check the product datasheet for detailed specifications.
2. Product Types: The kit is available in different packaging options (A, B, and C), each containing different components. Choose the packaging that best suits your needs, whether for research or clinical use.
3. Budget: Consider your budget when selecting the kit. While higher-priced kits may offer additional features or higher quality, ensure that the kit you choose provides the necessary performance for your application.
4. Intended Use: Determine the primary use of the kit, whether for clinical diagnostics, research, or quality control. This will help you select the most appropriate kit for your needs.

Purchasing the Aβ1-42 Detection Kit requires careful consideration of various factors. By understanding the product specifications, types, and your budget, you can make an informed decision that meets your needs. Whether for clinical diagnostics or research, this kit offers reliable performance and accurate results.

 Precautions

When using the Aβ1-42 Detection Kit, it is important to follow proper handling and storage procedures to ensure accurate results and maintain the integrity of the components.

1. Storage Conditions: Store the kit components at the recommended temperatures to maintain their stability and performance. Improper storage can lead to degradation of the reagents and affect the accuracy of the results.
2. Handling: Handle the kit components with care, especially the magnetic particle suspension and labeled working solution. Avoid exposure to light and extreme temperatures, as this can affect their performance.
3. Calibration: Regularly calibrate the kit using the provided calibrators to ensure accurate and consistent results. Follow the calibration procedure outlined in the product manual.
4. Quality Control: Use the included quality control materials to verify the performance of the kit. This helps ensure that the kit is functioning correctly and providing reliable results.
5. Disposal: Dispose of used kit components according to local regulations and guidelines. Proper disposal is essential to prevent contamination and ensure safety in the laboratory.

Proper handling and storage of the Aβ1-42 Detection Kit are crucial for obtaining accurate and reliable results. By following the recommended precautions, you can ensure the integrity of the kit components and maintain high standards in your laboratory work. Always adhere to the guidelines provided in the product manual to achieve the best outcomes.

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