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β2-Microglobulin Assay Reagent (Latex-Enhanced Immunoturbidimetric Method)
The β2-Microglobulin Assay Reagent consists of two main components: Reagent R1, a phosphate buffer solution (50mmol/L), and Reagent R2, a glycine buffer solution (50mmol/L) containing rabbit anti-human β2-MG antibody-sensitized latex particles (<0.3% w/v). Optional components include a calibrator (recombinant β2-microglobulin) and a control (recombinant β2-microglobulin), both traceable to the reference material NIBSC, UK, ENG, 3QG. It is crucial not to mix reagents from different batches.
Product English Name:
β2-Microglobulin Assay Reagent (Latex-Enhanced Immunoturbidimetric Method)
Alias:
β2-MG Assay Kit,Latex-Enhanced β2-Microglobulin Test
Intended Use:
This reagent is designed for the in vitro quantitative determination of β2-microglobulin (β2-MG) levels in human serum and urine. It is widely used in clinical laboratories to assess kidney function, monitor certain cancers, and evaluate immune system disorders.
Product Introduction

The β2-Microglobulin Assay Reagent is a highly sensitive and specific diagnostic tool used to measure β2-microglobulin levels in biological samples. Utilizing a latex-enhanced immunoturbidimetric method, it offers precise and reliable results, making it an essential component in clinical diagnostics.

1. The reagent features a latex-enhanced immunoturbidimetric method, which enhances sensitivity and specificity in detecting β2-microglobulin. This method ensures accurate quantification even at low concentrations, making it ideal for clinical applications.
2. The reagent is composed of two main components: Reagent R1, a phosphate buffer solution, and Reagent R2, a glycine buffer solution containing antibody-sensitized latex particles. Optional calibrators and controls are also available to ensure accuracy and traceability.
3. This reagent is primarily used for the quantitative determination of β2-microglobulin in human serum and urine. It is crucial in diagnosing and monitoring kidney diseases, certain cancers, and immune system disorders, providing valuable insights into patient health.

The β2-Microglobulin Assay Reagent, also known as the β2-MG Assay Kit, is a vital tool in clinical diagnostics. Its latex-enhanced immunoturbidimetric method ensures high sensitivity and specificity, making it indispensable for accurate β2-microglobulin measurement. With its precise composition and broad clinical applications, this reagent stands out as a reliable choice for healthcare professionals.

Main Features

The β2-Microglobulin Assay Reagent offers high sensitivity, specificity, and reliability in measuring β2-microglobulin levels. Its latex-enhanced immunoturbidimetric method ensures accurate results, making it a preferred choice in clinical diagnostics.

1. High Sensitivity: The latex-enhanced immunoturbidimetric method allows for the detection of low concentrations of β2-microglobulin, ensuring accurate results even in samples with minimal analyte levels.
2. Specificity: The use of rabbit anti-human β2-MG antibody-sensitized latex particles ensures that the assay specifically targets β2-microglobulin, reducing the risk of cross-reactivity with other proteins.
3. Reliability: The reagent's composition, including optional calibrators and controls, ensures consistent and reproducible results across different batches and laboratories.
4. Ease of Use: The assay is designed for straightforward application in clinical laboratories, with clear instructions and minimal preparation required.
5. Broad Clinical Applications: The reagent is used in various clinical settings, including nephrology, oncology, and immunology, to diagnose and monitor a range of conditions.

The β2-Microglobulin Assay Reagent is a robust diagnostic tool, offering high sensitivity, specificity, and reliability. Its ease of use and broad clinical applications make it an essential component in modern healthcare, providing accurate and timely results for patient care.

Clinical Applications

The β2-Microglobulin Assay Reagent is widely used in clinical settings to diagnose and monitor kidney diseases, certain cancers, and immune system disorders. Its accurate measurement of β2-microglobulin levels provides critical insights into patient health.

1. Kidney Disease Diagnosis: The reagent is used to assess kidney function by measuring β2-microglobulin levels in serum and urine, helping to diagnose conditions such as chronic kidney disease and renal tubular dysfunction.
2. Cancer Monitoring: Elevated β2-microglobulin levels are associated with certain cancers, including multiple myeloma and lymphoma. The reagent aids in monitoring disease progression and treatment efficacy.
3. Immune System Disorders: The assay is used to evaluate immune system disorders, such as HIV/AIDS, where β2-microglobulin levels can indicate disease activity and immune status.
4. Transplant Monitoring: The reagent is employed in post-transplant monitoring to detect early signs of organ rejection, as changes in β2-microglobulin levels can signal immune response.
5. Research Applications: Beyond clinical diagnostics, the reagent is used in research settings to study the role of β2-microglobulin in various diseases and biological processes.

The β2-Microglobulin Assay Reagent plays a crucial role in clinical diagnostics, offering valuable insights into kidney function, cancer progression, and immune system health. Its versatility and accuracy make it an indispensable tool for healthcare professionals and researchers alike.

Purchasing Guide

When purchasing the β2-Microglobulin Assay Reagent, consider product specifications, types, budget, and intended use to ensure it meets your clinical or research needs.

1. Product Specifications: Evaluate the reagent's sensitivity, specificity, and reliability. Ensure it meets the required standards for your laboratory's diagnostic needs.
2. Product Types: Choose between different formulations, such as liquid or lyophilized reagents, based on your laboratory's storage and handling capabilities.
3. Budget Considerations: Assess the cost-effectiveness of the reagent, including the price per test and the availability of bulk purchasing options.
4. Intended Use: Consider the specific clinical or research applications for which the reagent will be used, ensuring it aligns with your diagnostic or experimental goals.

Purchasing the β2-Microglobulin Assay Reagent requires careful consideration of product specifications, types, budget, and intended use. By selecting the right reagent for your needs, you can ensure accurate and reliable results in your clinical or research applications.

 Precautions

Proper handling and storage of the β2-Microglobulin Assay Reagent are essential to ensure accurate results and maintain reagent integrity. Follow all safety and usage guidelines provided by the manufacturer.

1. Storage Conditions: Store the reagent at the recommended temperature, typically between 2-8°C, to maintain its stability and effectiveness.
2. Handling Precautions: Use appropriate personal protective equipment (PPE) when handling the reagent, including gloves and lab coats, to avoid contamination and exposure.
3. Reagent Preparation: Follow the manufacturer's instructions for preparing and mixing reagents to ensure accurate and consistent results.
4. Instrument Calibration: Regularly calibrate the diagnostic instruments used with the reagent to maintain accuracy and reliability in test results.
5. Disposal: Dispose of used reagents and samples according to local regulations and laboratory safety protocols to prevent environmental contamination.

Handling the β2-Microglobulin Assay Reagent with care is crucial for maintaining its effectiveness and ensuring accurate diagnostic results. By adhering to storage, handling, and disposal guidelines, you can protect both the reagent's integrity and the safety of laboratory personnel.

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