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α1-Microglobulin Detection Kit (Latex Enhanced Immunoturbidimetric Method)
The α1-Microglobulin Detection Kit is composed of two main reagents: R1 and R2. R1 contains Tris buffer (pH 7.2, 20 mmol/L), sodium chloride (100 mmol/L), and polyethylene glycol 6000 (35 g/L). R2 includes particles coated with anti-human α1-microglobulin antibodies (100 ml/L) and Proclin 300 preservative (0.01%). The kit also includes calibrators and controls made of recombinant human α1-microglobulin, with concentrations ranging from 20 mg/L to 150 mg/L.
Product English Name:
α1-Microglobulin Detection Kit (Latex Enhanced Immunoturbidimetric Method)
Alias:
α1-MG Kit,Immunoturbidimetric α1-Microglobulin Assay
Intended Use:
This kit is designed for the in vitro quantitative determination of α1-microglobulin (α1-MG) levels in human serum. It is widely used in clinical laboratories to assess kidney function and monitor conditions related to renal impairment.
Product Introduction

The α1-Microglobulin Detection Kit utilizes the latex-enhanced immunoturbidimetric method to accurately measure α1-microglobulin levels in serum. This method is known for its high sensitivity and specificity, making it a reliable tool for clinical diagnostics. The kit is easy to use, with a straightforward protocol that ensures consistent results. It is an essential tool for laboratories focusing on renal health and related disorders.

1. The kit features a latex-enhanced immunoturbidimetric method, which enhances the sensitivity and accuracy of α1-microglobulin detection. This method is particularly effective in detecting low concentrations of the protein, making it suitable for early diagnosis of renal diseases.
2. The composition of the kit includes two main reagents: R1 and R2. R1 contains a Tris buffer system, sodium chloride, and polyethylene glycol, which stabilize the reaction environment. R2 consists of antibody-coated particles and a preservative, ensuring the longevity and reliability of the reagents.
3. The primary use of this kit is to measure α1-microglobulin levels in serum, which is a critical marker for kidney function. Elevated levels of α1-microglobulin can indicate renal tubular damage, making this kit an invaluable tool for diagnosing and monitoring kidney-related conditions.

The α1-Microglobulin Detection Kit, also known as the α1-MG Kit, is a specialized tool designed for the precise measurement of α1-microglobulin in serum. Its unique latex-enhanced immunoturbidimetric method ensures high accuracy and sensitivity, making it a preferred choice for clinical laboratories. The kit's composition, including its carefully formulated reagents, guarantees reliable performance, while its primary use in assessing kidney function underscores its importance in renal health diagnostics.

Main Features

The α1-Microglobulin Detection Kit offers high sensitivity and specificity in detecting α1-microglobulin levels, making it an essential tool for clinical diagnostics, particularly in renal health.

1. The kit employs a latex-enhanced immunoturbidimetric method, which significantly improves the detection sensitivity of α1-microglobulin, even at low concentrations.
2. It includes a stable buffer system (R1) that ensures consistent reaction conditions, enhancing the reliability of the results.
3. The antibody-coated particles in R2 are specifically designed to bind to α1-microglobulin, ensuring high specificity in the detection process.
4. The kit comes with calibrators and controls that allow for accurate quantification of α1-microglobulin levels, ensuring the precision of the assay.
5. The entire process is streamlined for ease of use, with a simple protocol that minimizes the risk of user error and ensures consistent results across different laboratories.

The α1-Microglobulin Detection Kit stands out for its high sensitivity, specificity, and ease of use. Its latex-enhanced immunoturbidimetric method ensures accurate detection of α1-microglobulin, while its stable reagents and straightforward protocol make it a reliable choice for clinical laboratories. The inclusion of calibrators and controls further enhances the precision of the assay, making it an indispensable tool for renal health diagnostics.

Clinical Applications

The α1-Microglobulin Detection Kit is widely used in clinical settings to assess kidney function and diagnose renal diseases, particularly those involving tubular damage.

1. The kit is commonly used in nephrology to monitor patients with chronic kidney disease (CKD), as elevated α1-microglobulin levels can indicate tubular damage.
2. It is also employed in the diagnosis of acute kidney injury (AKI), where early detection of tubular damage is crucial for effective treatment.
3. The kit is used in research settings to study the role of α1-microglobulin in various renal pathologies, providing valuable insights into disease mechanisms.
4. In clinical laboratories, the kit is used for routine screening of patients at risk of renal impairment, such as those with diabetes or hypertension.
5. The kit is also utilized in the assessment of kidney transplant recipients, where monitoring α1-microglobulin levels can help detect early signs of rejection or other complications.

The α1-Microglobulin Detection Kit plays a critical role in clinical nephrology, offering a reliable method for assessing kidney function and diagnosing renal diseases. Its ability to detect tubular damage early makes it particularly valuable in the management of chronic kidney disease and acute kidney injury. The kit's applications extend to research and routine screening, making it a versatile tool in both clinical and laboratory settings.

Purchasing Guide

When purchasing the α1-Microglobulin Detection Kit, it is important to consider factors such as product specifications, budget, and intended use to ensure the best fit for your laboratory's needs.

1. Product specifications: Ensure that the kit meets your laboratory's requirements in terms of sensitivity, specificity, and ease of use. Check the concentration range of the calibrators and controls to ensure they align with your testing needs.
2. Product type: Consider whether you need a kit for routine screening or specialized research. Some kits may offer additional features, such as extended shelf life or enhanced stability, which could be beneficial depending on your usage.
3. Budget: Evaluate the cost-effectiveness of the kit, taking into account the number of tests it can perform and the overall value it provides. Consider any additional costs, such as shipping or storage requirements.
4. Usage scenarios: Determine the specific applications for which you will use the kit, such as routine patient screening, research, or specialized diagnostics. This will help you choose a kit that best suits your laboratory's workflow and testing volume.

Purchasing the α1-Microglobulin Detection Kit requires careful consideration of product specifications, type, budget, and intended use. By aligning these factors with your laboratory's needs, you can ensure that you select a kit that offers the best performance and value. Whether for routine screening or specialized research, the right kit will enhance your laboratory's diagnostic capabilities and contribute to better patient outcomes.

 Precautions

Proper handling and storage of the α1-Microglobulin Detection Kit are essential to ensure accurate results and maintain the integrity of the reagents.

1. Storage: Store the kit at the recommended temperature, typically between 2-8°C, to maintain the stability of the reagents. Avoid freezing the kit, as this can damage the antibody-coated particles.
2. Handling: Always use clean, sterile pipettes and containers to avoid contamination. Follow the manufacturer's instructions for proper handling of the reagents to ensure accurate results.
3. Calibration: Regularly calibrate the kit using the provided calibrators to ensure the accuracy of the assay. Avoid using expired calibrators or controls, as this can lead to inaccurate results.
4. Disposal: Dispose of used reagents and containers according to local regulations for biohazardous waste. Ensure that all waste is properly labeled and handled to prevent contamination.
5. Training: Ensure that all personnel using the kit are properly trained in its use and understand the importance of following the protocol precisely to avoid errors.

The α1-Microglobulin Detection Kit requires careful handling and storage to ensure accurate and reliable results. Proper storage conditions, handling techniques, and regular calibration are essential to maintain the integrity of the reagents. Additionally, proper disposal of waste and adequate training of personnel are crucial to prevent contamination and ensure the safety of the laboratory environment. By following these precautions, you can maximize the performance and longevity of the kit.

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