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N-Acetyl-β-D-Glucosaminidase Assay Kit (MNP-GlcNAc Method)
The N-Acetyl-β-D-Glucosaminidase Assay Kit is composed of two main reagents: Reagent 1 (R1) and Reagent 2 (R2). R1 contains a liquid Tris buffer, MNP-GlcNAc, HCl, citric acid, and phosphate. R2 consists of a liquid Na2CO3 buffer. Optional components include calibrators and controls, which are lyophilized powders containing human serum, sodium dihydrogen phosphate, disodium hydrogen phosphate, sodium chloride, preservatives, and stabilizers.
Product English Name:
N-Acetyl-β-D-Glucosaminidase Assay Kit (MNP-GlcNAc Method)
Alias:
NAG Assay Kit,MNP-GlcNAc Kit
Intended Use:
This kit is designed for the quantitative determination of N-Acetyl-β-D-Glucosaminidase (NAG) activity in human serum or urine samples. It is widely used in clinical laboratories to assess renal function and detect early kidney damage.
Product Introduction

The N-Acetyl-β-D-Glucosaminidase Assay Kit is a specialized diagnostic tool used to measure the activity of the enzyme NAG in biological samples. This enzyme is a marker for renal tubular damage, making the kit essential for early detection of kidney disorders. The kit employs the MNP-GlcNAc method, which is known for its accuracy and reliability in clinical settings.

1. The kit features a highly sensitive and specific assay method, ensuring precise measurement of NAG activity. It is designed for use in automated analyzers, providing consistent and reproducible results.
2. The composition includes carefully balanced reagents that optimize the enzymatic reaction. The inclusion of optional calibrators and controls allows for accurate calibration and quality assurance in clinical laboratories.
3. The primary use of the kit is in the diagnosis and monitoring of kidney diseases. It is particularly valuable in detecting early stages of renal damage, where traditional markers may not be as sensitive.

The N-Acetyl-β-D-Glucosaminidase Assay Kit, also known as the NAG Assay Kit, is a vital tool in clinical diagnostics. Its precise measurement capabilities and reliable performance make it indispensable for assessing renal health. Whether you're a clinician or a researcher, this kit offers the accuracy and consistency needed for effective kidney function evaluation.

Main Features

The N-Acetyl-β-D-Glucosaminidase Assay Kit offers high sensitivity, specificity, and reliability in measuring NAG activity. It is designed for use in automated analyzers, ensuring consistent results in clinical laboratories.

1. High Sensitivity: The kit detects low levels of NAG activity, making it ideal for early detection of renal damage.
2. Specificity: The MNP-GlcNAc method ensures that the assay is specific to NAG, reducing the risk of cross-reactivity with other enzymes.
3. Automation Compatibility: Designed for use with automated analyzers, the kit streamlines the diagnostic process, saving time and reducing manual errors.
4. Quality Assurance: Optional calibrators and controls provide a means to verify the accuracy and precision of the assay.
5. Clinical Relevance: The kit is widely used in clinical settings to monitor kidney function and detect early signs of renal disease.

The N-Acetyl-β-D-Glucosaminidase Assay Kit stands out for its high sensitivity, specificity, and compatibility with automated systems. Its ability to provide reliable and accurate results makes it a cornerstone in the diagnosis and monitoring of kidney diseases.

Clinical Applications

The N-Acetyl-β-D-Glucosaminidase Assay Kit is primarily used in clinical laboratories to assess renal function and detect early kidney damage. It is also employed in research settings to study the role of NAG in various diseases.

1. Renal Function Assessment: The kit is used to measure NAG activity in serum and urine, providing insights into kidney health.
2. Early Detection of Kidney Damage: Elevated NAG levels are an early indicator of renal tubular damage, making the kit valuable for early diagnosis.
3. Monitoring Disease Progression: The kit is used to track changes in NAG activity over time, helping clinicians monitor the progression of kidney diseases.
4. Research Applications: Researchers use the kit to study the role of NAG in various pathological conditions, including diabetes and hypertension.
5. Quality Control in Laboratories: The kit's optional calibrators and controls ensure the accuracy and reliability of NAG measurements in clinical settings.

The N-Acetyl-β-D-Glucosaminidase Assay Kit is a versatile tool in both clinical and research settings. Its ability to accurately measure NAG activity makes it indispensable for assessing renal function and detecting early signs of kidney damage.

Purchasing Guide

When purchasing the N-Acetyl-β-D-Glucosaminidase Assay Kit, consider factors such as product specifications, types, budget, and intended use to ensure it meets your laboratory's needs.

1. Product Specifications: Review the kit's components, including reagents, calibrators, and controls, to ensure they meet your laboratory's requirements.
2. Product Types: Choose between different kit formats, such as manual or automated, based on your laboratory's workflow and equipment.
3. Budget Considerations: Evaluate the cost of the kit, including any additional expenses for calibrators, controls, and shipping.
4. Usage Scenarios: Consider the specific applications for which the kit will be used, such as clinical diagnostics or research, to ensure it aligns with your needs.

Purchasing the N-Acetyl-β-D-Glucosaminidase Assay Kit requires careful consideration of product specifications, types, budget, and intended use. By taking these factors into account, you can ensure that the kit meets your laboratory's needs and delivers reliable results.

 Precautions

Proper handling and storage of the N-Acetyl-β-D-Glucosaminidase Assay Kit are essential to ensure accurate results and maintain the integrity of the reagents.

1. Storage Conditions: Store the kit at the recommended temperature to prevent degradation of the reagents.
2. Handling Precautions: Use gloves and other protective equipment when handling the reagents to avoid contamination.
3. Expiration Date: Always check the expiration date before using the kit to ensure the reagents are still effective.
4. Calibration: Regularly calibrate the assay using the provided calibrators to maintain accuracy.
5. Disposal: Dispose of used reagents and materials according to local regulations to ensure safety and environmental compliance.

The N-Acetyl-β-D-Glucosaminidase Assay Kit requires careful handling and storage to ensure accurate and reliable results. By following the recommended precautions, you can maintain the integrity of the reagents and achieve consistent performance in your laboratory.

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