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KRAS Gene Mutation Detection Kit (PCR-Fluorescence Probe Method)
The KRAS Gene Mutation Detection Kit is composed of two main packaging types: a bulk pack and a single-use pack. The bulk pack includes quality control samples (KRAS positive and negative controls) and PCR detection reagents (KRAS external control reaction solution, G12D reaction solution, G12A reaction solution, G12V reaction solution, G12S reaction solution, G12R reaction solution, G12C reaction solution, G13D reaction solution, and KRAS enzyme system). The single-use pack contains quality control samples (KRAS positive and negative controls) and PCR detection reagents (KRAS 8-tube detection reaction plate).
Product English Name:
KRAS Gene Mutation Detection Kit (PCR-Fluorescence Probe Method)
Alias:
KRAS Mutation Test Kit,KRAS PCR Kit
Intended Use:
This kit is designed for the qualitative detection of KRAS gene mutations at codon 12 (G12D, G12A, G12V, G12S, G12R, G12C) and codon 13 (G13D) in paraffin-embedded human colorectal cancer tissue samples. It is a crucial tool for identifying specific genetic mutations that may influence treatment decisions in cancer therapy.
Product Introduction

The KRAS Gene Mutation Detection Kit is a state-of-the-art diagnostic tool designed to identify specific mutations in the KRAS gene, which are commonly associated with colorectal cancer. Utilizing the PCR-fluorescence probe method, this kit offers high sensitivity and specificity, making it an essential component in modern molecular diagnostics. The kit is available in both bulk and single-use formats, catering to different laboratory needs.

1. The KRAS Gene Mutation Detection Kit is characterized by its high sensitivity and specificity, ensuring accurate detection of KRAS mutations. The use of fluorescence probes allows for real-time monitoring of the PCR process, enhancing the reliability of the results.
2. The kit is composed of quality control samples and a range of PCR detection reagents, including specific reaction solutions for different KRAS mutations. The bulk pack is designed for high-throughput laboratories, while the single-use pack is ideal for smaller-scale operations.
3. This kit is primarily used in the detection of KRAS mutations in colorectal cancer tissue samples. Identifying these mutations is crucial for determining the most effective treatment strategies, particularly in the context of targeted therapies.

The KRAS Gene Mutation Detection Kit, also known as the KRAS Mutation Test Kit, is a vital tool in the field of molecular diagnostics. Its ability to accurately detect specific KRAS mutations makes it indispensable for clinicians and researchers working in oncology. The kit's comprehensive composition and user-friendly design ensure that it meets the diverse needs of modern laboratories.

Main Features

The KRAS Gene Mutation Detection Kit offers a range of features designed to enhance the accuracy and efficiency of KRAS mutation detection. These include high sensitivity, specificity, and the ability to detect multiple mutations simultaneously.

1. High Sensitivity: The kit is capable of detecting low levels of KRAS mutations, ensuring accurate results even in samples with minimal genetic material.
2. Specificity: The use of fluorescence probes allows for the specific detection of KRAS mutations, reducing the risk of false positives.
3. Multiplex Detection: The kit can detect multiple KRAS mutations simultaneously, making it a versatile tool for comprehensive genetic analysis.
4. Real-Time Monitoring: The fluorescence probes enable real-time monitoring of the PCR process, providing immediate feedback on the progress of the reaction.
5. User-Friendly Design: The kit is designed for ease of use, with clear instructions and a straightforward workflow that minimizes the risk of user error.

The KRAS Gene Mutation Detection Kit stands out for its high sensitivity, specificity, and ability to detect multiple mutations simultaneously. These features make it an invaluable tool for clinicians and researchers, enabling them to make informed decisions about cancer treatment strategies. The kit's user-friendly design further enhances its appeal, making it accessible to a wide range of laboratory settings.

Clinical Applications

The KRAS Gene Mutation Detection Kit is widely used in clinical settings for the detection of KRAS mutations in colorectal cancer patients. Its applications extend to research and development, where it is used to study the genetic basis of cancer and develop targeted therapies.

1. Clinical Diagnostics: The kit is used in clinical laboratories to detect KRAS mutations in colorectal cancer patients, helping to guide treatment decisions.
2. Research and Development: Researchers use the kit to study the genetic mutations associated with cancer, contributing to the development of new therapies.
3. Personalized Medicine: The detection of KRAS mutations allows for the customization of treatment plans based on the genetic profile of the patient.
4. Clinical Trials: The kit is used in clinical trials to monitor the effectiveness of new cancer treatments and to identify patients who may benefit from targeted therapies.
5. Quality Control: The kit is used in quality control processes to ensure the accuracy and reliability of genetic testing in clinical laboratories.

The KRAS Gene Mutation Detection Kit has a wide range of clinical applications, from guiding treatment decisions in colorectal cancer patients to contributing to the development of new therapies in research settings. Its ability to detect specific genetic mutations makes it a key tool in the advancement of personalized medicine and the improvement of cancer treatment outcomes.

Purchasing Guide

The KRAS Gene Mutation Detection Kit is available in both bulk and single-use formats, catering to different laboratory needs. When purchasing the kit, it is important to consider factors such as product specifications, budget, and intended use.

1. Product Specifications: The kit is available in two formats: a bulk pack for high-throughput laboratories and a single-use pack for smaller-scale operations. It is important to choose the format that best suits your laboratory's needs.
2. Product Type: The kit is designed for the detection of KRAS mutations in colorectal cancer tissue samples. Ensure that the kit is compatible with your laboratory's equipment and workflows.
3. Budget: The cost of the kit may vary depending on the format and quantity purchased. Consider your laboratory's budget when making a purchasing decision.
4. Intended Use: The kit is intended for use in clinical diagnostics, research, and quality control. Ensure that the kit meets the specific requirements of your intended application.

When purchasing the KRAS Gene Mutation Detection Kit, it is important to consider factors such as product specifications, budget, and intended use. The kit is available in both bulk and single-use formats, making it suitable for a wide range of laboratory settings. By carefully evaluating these factors, you can ensure that you select the kit that best meets your laboratory's needs.

 Precautions

When using the KRAS Gene Mutation Detection Kit, it is important to follow the manufacturer's instructions carefully to ensure accurate results. Proper handling and storage of the kit components are also crucial to maintain their effectiveness.

1. Proper Storage: The kit components should be stored at the recommended temperature to maintain their stability and effectiveness. Improper storage can lead to degradation of the reagents and inaccurate results.
2. Handling: Care should be taken when handling the kit components to avoid contamination. Use sterile techniques and wear appropriate protective equipment.
3. Calibration: Ensure that all equipment used with the kit is properly calibrated to avoid errors in the detection process.
4. Quality Control: Regularly perform quality control checks to ensure the accuracy and reliability of the results.
5. Disposal: Dispose of used kit components according to local regulations and guidelines to prevent environmental contamination.

Using the KRAS Gene Mutation Detection Kit requires careful attention to detail to ensure accurate and reliable results. Proper storage, handling, and disposal of the kit components are essential to maintain their effectiveness and prevent contamination. By following the manufacturer's instructions and adhering to best practices, you can maximize the performance of the kit and achieve the best possible outcomes in your genetic testing.

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