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Ki-67 Antibody Reagent (Immunohistochemistry)
The Ki-67 Antibody Reagent is composed of Ki-67 antibody working solution and a blank control reagent. It is specifically designed for the qualitative detection of Ki-67 in formalin-fixed, paraffin-embedded tissue sections. The reagent is used in immunohistochemistry to identify proliferating cells, which is crucial in cancer research and diagnosis.
Product English Name:
Ki-67 Antibody Reagent (Immunohistochemistry)
Alias:
Ki-67 IHC Reagent,Ki-67 Detection Kit
Intended Use:
This kit is used for the qualitative detection of Ki-67 in tissue sections that have been fixed in 10% neutral buffered formalin and embedded in paraffin. It is primarily utilized in research and clinical settings to assess cell proliferation, which is a key indicator in cancer diagnosis and prognosis.
Product Introduction

The Ki-67 Antibody Reagent is a specialized tool used in immunohistochemistry to detect the presence of Ki-67, a protein associated with cell proliferation. This reagent is essential for researchers and clinicians who need to assess the growth rate of cells, particularly in cancer studies. The kit includes a Ki-67 antibody working solution and a blank control reagent, ensuring accurate and reliable results.

1. The Ki-67 Antibody Reagent is known for its high specificity and sensitivity, making it a reliable choice for detecting proliferating cells in tissue samples. It is designed to work with formalin-fixed, paraffin-embedded tissues, which are commonly used in pathology labs.
2. The reagent consists of two main components: the Ki-67 antibody working solution and a blank control reagent. The antibody solution is optimized for immunohistochemical staining, while the blank control ensures that any non-specific binding is accounted for, leading to more accurate results.
3. The primary use of this reagent is in the qualitative detection of Ki-67 in tissue sections. It is widely used in cancer research to determine the proliferation index of tumors, which helps in assessing the aggressiveness of the cancer and guiding treatment decisions.

The Ki-67 Antibody Reagent, also known as the Ki-67 IHC Reagent, is a vital tool in the field of immunohistochemistry. It is specifically designed to detect Ki-67, a marker of cell proliferation, in tissue samples. The reagent's high specificity and sensitivity make it a reliable choice for researchers and clinicians alike. Its use in cancer research and diagnosis underscores its importance in modern medicine.

Main Features

The Ki-67 Antibody Reagent offers high specificity and sensitivity in detecting proliferating cells. It is designed for use with formalin-fixed, paraffin-embedded tissues, making it a versatile tool in pathology and cancer research.

1. The Ki-67 Antibody Reagent is highly specific to the Ki-67 protein, ensuring accurate detection of proliferating cells. This specificity is crucial in cancer research, where precise identification of cell proliferation is necessary.
2. The reagent is optimized for use with formalin-fixed, paraffin-embedded tissues, which are the standard in pathology labs. This compatibility ensures that the reagent can be used in a wide range of clinical and research settings.
3. The kit includes a blank control reagent, which helps in identifying and accounting for any non-specific binding. This feature enhances the accuracy of the results, making the reagent more reliable.
4. The Ki-67 Antibody Reagent is easy to use, with a straightforward protocol that can be followed by both experienced researchers and those new to immunohistochemistry.
5. The reagent is stable and has a long shelf life, ensuring that it can be stored and used over an extended period without losing its effectiveness.

The Ki-67 Antibody Reagent is a powerful tool in the detection of cell proliferation. Its high specificity, compatibility with standard tissue processing methods, and ease of use make it an essential reagent in cancer research and diagnosis. The inclusion of a blank control reagent further enhances its reliability, ensuring accurate and consistent results.

Clinical Applications

The Ki-67 Antibody Reagent is widely used in clinical applications, particularly in cancer diagnosis and research. It helps in assessing the proliferation index of tumors, which is crucial for determining the aggressiveness of the cancer and guiding treatment decisions.

1. In clinical pathology, the Ki-67 Antibody Reagent is used to assess the proliferation index of various cancers, including breast, prostate, and lung cancers. This information is vital for determining the prognosis and guiding treatment strategies.
2. The reagent is also used in research settings to study the effects of different treatments on cell proliferation. This helps in understanding the mechanisms of action of various drugs and therapies.
3. In surgical pathology, the Ki-67 Antibody Reagent is used to evaluate the proliferation rate of tumors, which can help in determining the need for adjuvant therapy after surgery.
4. The reagent is also used in the development of new cancer therapies, where understanding the proliferation rate of cancer cells is crucial for evaluating the effectiveness of new treatments.
5. In addition to cancer research, the Ki-67 Antibody Reagent is used in other fields of medicine, such as dermatology and hematology, where cell proliferation plays a key role in disease progression.

The Ki-67 Antibody Reagent is a versatile tool in clinical applications, particularly in cancer diagnosis and research. Its ability to accurately assess the proliferation index of tumors makes it invaluable in determining the aggressiveness of cancer and guiding treatment decisions. Its use extends beyond cancer research, making it a valuable asset in various fields of medicine.

Purchasing Guide

When purchasing the Ki-67 Antibody Reagent, it is important to consider factors such as product specifications, types, budget, and intended use. This guide provides essential information to help you make an informed decision.

1. Product specifications: Ensure that the Ki-67 Antibody Reagent meets the required specifications for your research or clinical needs. This includes checking the sensitivity, specificity, and compatibility with your tissue processing methods.
2. Product types: There are different types of Ki-67 Antibody Reagents available, each designed for specific applications. Choose the one that best suits your needs, whether it's for research, clinical diagnosis, or both.
3. Budget: Consider your budget when purchasing the Ki-67 Antibody Reagent. While it is important to choose a high-quality product, it is also essential to ensure that it fits within your financial constraints.
4. Intended use: Determine the primary use of the Ki-67 Antibody Reagent, whether it is for research, clinical diagnosis, or both. This will help you choose the right product and ensure that it meets your specific requirements.

Purchasing the Ki-67 Antibody Reagent requires careful consideration of various factors, including product specifications, types, budget, and intended use. By taking these factors into account, you can ensure that you choose the right product for your needs, whether it's for research, clinical diagnosis, or both.

 Precautions

When using the Ki-67 Antibody Reagent, it is important to follow proper handling and storage procedures to ensure accurate results and maintain the reagent's effectiveness.

1. Always handle the Ki-67 Antibody Reagent with care, following the manufacturer's instructions for storage and use. Improper handling can lead to inaccurate results or degradation of the reagent.
2. Store the reagent at the recommended temperature to maintain its stability and effectiveness. Exposure to extreme temperatures can compromise the reagent's performance.
3. Use the reagent within its expiration date to ensure optimal results. Using expired reagents can lead to unreliable data and potentially compromise your research or clinical diagnosis.
4. Follow the recommended protocol for immunohistochemical staining to ensure accurate and consistent results. Deviating from the protocol can lead to variability in staining intensity and interpretation.
5. Dispose of the reagent and any waste materials according to local regulations and guidelines. Proper disposal is essential to prevent environmental contamination and ensure safety.

Proper handling, storage, and use of the Ki-67 Antibody Reagent are crucial for obtaining accurate and reliable results. By following the manufacturer's instructions and adhering to recommended protocols, you can ensure the reagent's effectiveness and maintain the integrity of your research or clinical diagnosis. Proper disposal of the reagent and waste materials is also essential to prevent environmental contamination and ensure safety.

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