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K-ras Gene Mutation Typing Detection Kit (Fluorescence PCR Method)
The kit consists of Reaction Solution 0 (ref), Reaction Solution 1 (13Asp), Reaction Solution 2 (12Asp), Reaction Solution 3 (12Val), Reaction Solution 4 (12Ala), Reaction Solution 5 (12Arg), Reaction Solution 6 (12Ser), Reaction Solution 7 (12Cys), internal control, DNA polymerase, and positive control. Detailed information can be found in the manual.
Product English Name:
K-ras Gene Mutation Typing Detection Kit (Fluorescence PCR Method)
Alias:
K-ras Mutation Detection Kit,K-ras Genotyping Kit
Intended Use:
This kit is designed for the qualitative detection of seven common mutations in codons 12 and 13 of the K-ras gene in DNA extracted from formalin-fixed, paraffin-embedded tumor tissues of lung or colorectal cancer patients. It can also identify the types of mutations.
Product Introduction

The K-ras Gene Mutation Typing Detection Kit (Fluorescence PCR Method) is a specialized diagnostic tool used to identify specific mutations in the K-ras gene, which are commonly associated with lung and colorectal cancers. This kit employs fluorescence PCR technology to provide accurate and reliable results, making it an essential tool for oncologists and researchers.

1. The kit is designed to detect seven common mutations in the K-ras gene, specifically in codons 12 and 13. These mutations are critical in understanding the progression and treatment options for lung and colorectal cancers.
2. The kit includes multiple reaction solutions, each tailored to detect specific mutations. It also contains an internal control, DNA polymerase, and a positive control to ensure the accuracy and reliability of the results.
3. The primary use of this kit is in the qualitative detection of K-ras gene mutations in DNA extracted from formalin-fixed, paraffin-embedded tumor tissues. This helps in identifying the type of mutation, which is crucial for personalized cancer treatment.

The K-ras Gene Mutation Typing Detection Kit is a vital tool in the fight against cancer. Its ability to accurately detect and identify specific mutations in the K-ras gene makes it indispensable for oncologists and researchers. The kit's comprehensive design, including multiple reaction solutions and controls, ensures reliable results, aiding in the development of personalized treatment plans for patients.

Main Features

The K-ras Gene Mutation Typing Detection Kit offers precise detection of K-ras gene mutations, essential for cancer diagnosis and treatment planning.

1. The kit provides high sensitivity and specificity in detecting K-ras gene mutations, ensuring accurate results.
2. It includes multiple reaction solutions, each designed to detect specific mutations, enhancing the kit's versatility.
3. The inclusion of an internal control and positive control ensures the reliability and accuracy of the test results.
4. The kit is compatible with DNA extracted from formalin-fixed, paraffin-embedded tumor tissues, making it suitable for a wide range of clinical samples.
5. The fluorescence PCR method used in the kit allows for rapid and efficient detection of mutations, facilitating timely diagnosis and treatment.

The K-ras Gene Mutation Typing Detection Kit stands out for its precision and reliability. Its comprehensive design, including multiple reaction solutions and controls, ensures accurate detection of K-ras gene mutations. This kit is an invaluable tool for oncologists, providing critical information for personalized cancer treatment.

Clinical Applications

The K-ras Gene Mutation Typing Detection Kit is widely used in clinical settings for the diagnosis and treatment planning of lung and colorectal cancers.

1. The kit is used to detect K-ras gene mutations in lung cancer patients, aiding in the selection of appropriate targeted therapies.
2. In colorectal cancer, the kit helps identify specific mutations that may influence the choice of chemotherapy or other treatments.
3. The kit is also used in research settings to study the role of K-ras mutations in cancer progression and treatment resistance.
4. Clinicians use the kit to monitor the effectiveness of treatments by tracking changes in K-ras mutation status over time.
5. The kit's ability to detect multiple mutations simultaneously makes it a valuable tool for comprehensive cancer diagnostics.

The K-ras Gene Mutation Typing Detection Kit is a cornerstone in the clinical management of lung and colorectal cancers. Its ability to accurately detect and identify specific mutations provides clinicians with the information needed to tailor treatments to individual patients, improving outcomes and advancing cancer research.

Purchasing Guide

When purchasing the K-ras Gene Mutation Typing Detection Kit, consider product specifications, types, budget, and intended use to ensure it meets your clinical or research needs.

1. Evaluate the product parameters, such as sensitivity, specificity, and compatibility with different sample types, to ensure it meets your diagnostic requirements.
2. Consider the different types of kits available, including those with varying numbers of reaction solutions, to find the one that best suits your needs.
3. Determine your budget and compare prices from different suppliers to find a cost-effective solution without compromising on quality.
4. Assess the intended use of the kit, whether for clinical diagnostics or research, to ensure it aligns with your objectives and provides the necessary features.

Purchasing the K-ras Gene Mutation Typing Detection Kit requires careful consideration of various factors, including product specifications, types, budget, and intended use. By evaluating these aspects, you can select a kit that meets your clinical or research needs, ensuring accurate and reliable results.

 Precautions

Proper handling and storage of the K-ras Gene Mutation Typing Detection Kit are essential to ensure accurate results and maintain product integrity.

1. Always follow the manufacturer's instructions for storage and handling to prevent contamination and degradation of the reagents.
2. Ensure that all equipment used with the kit, such as pipettes and PCR machines, is properly calibrated and maintained to avoid errors in results.
3. Use appropriate personal protective equipment (PPE) when handling the kit to protect against potential biohazards.
4. Regularly check the expiration dates of the reagents and replace any expired components to ensure the reliability of the test results.
5. Dispose of all waste materials according to local regulations and guidelines to prevent environmental contamination and ensure safety.

The K-ras Gene Mutation Typing Detection Kit requires careful handling and storage to maintain its effectiveness. By following the manufacturer's instructions, using proper equipment, and adhering to safety protocols, you can ensure accurate results and protect both the integrity of the product and the safety of the users.

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