The INFORM Chromosome 17 Probe is a specialized diagnostic tool used in molecular pathology to identify chromosomal abnormalities, particularly in chromosome 17. It is essential for detecting genetic alterations in breast cancer tissues, providing critical insights for diagnosis and treatment planning. The probe is designed for high specificity and sensitivity, ensuring reliable results in clinical and research settings.

1. The INFORM Chromosome 17 Probe is characterized by its high specificity and sensitivity, making it an invaluable tool for detecting chromosomal abnormalities. Its DNP-labeled design ensures clear and precise hybridization signals, which are crucial for accurate diagnosis.
2. The probe is composed of a 10 mL reagent bottle containing approximately 2 μg/mL of DNP-labeled Chromosome 17 probe, formulated in a hybridization buffer with formamide. This unique composition ensures stability and effectiveness in various laboratory conditions.
3. The primary use of the INFORM Chromosome 17 Probe is to detect the ploidy status of chromosome 17 in formalin-fixed, paraffin-embedded human breast cancer tissue specimens. This application is vital for understanding genetic alterations in cancer and guiding treatment decisions.

The INFORM Chromosome 17 Probe, also known as the Chromosome 17 Detection Probe, is a critical tool in molecular pathology. Its high specificity and sensitivity, combined with its unique composition, make it indispensable for detecting chromosomal abnormalities in breast cancer tissues. This probe not only aids in accurate diagnosis but also provides valuable insights for treatment planning.

The INFORM Chromosome 17 Probe offers high specificity and sensitivity for detecting chromosomal abnormalities, particularly in chromosome 17. Its DNP-labeled design ensures clear hybridization signals, making it a reliable tool for clinical and research applications.

1. The probe's high specificity ensures accurate detection of chromosome 17 abnormalities, reducing the risk of false positives and negatives in diagnostic tests.
2. Its sensitivity allows for the detection of even minor chromosomal alterations, providing detailed insights into genetic changes in cancer tissues.
3. The DNP-labeled design of the probe ensures clear and precise hybridization signals, which are essential for accurate interpretation of results.
4. The probe is formulated in a hybridization buffer with formamide, ensuring stability and effectiveness in various laboratory conditions.
5. The INFORM Chromosome 17 Probe is easy to use, with a straightforward protocol that can be integrated into existing laboratory workflows.

The INFORM Chromosome 17 Probe stands out for its high specificity, sensitivity, and ease of use. Its DNP-labeled design and stable formulation make it a reliable choice for detecting chromosomal abnormalities in clinical and research settings. This probe is an essential tool for accurate diagnosis and treatment planning in oncology.

The INFORM Chromosome 17 Probe is widely used in clinical settings to detect chromosomal abnormalities in breast cancer tissues. Its applications include diagnostic testing, research studies, and treatment planning, providing critical insights into genetic alterations.

1. In diagnostic testing, the probe is used to assess the ploidy status of chromosome 17 in breast cancer tissues, aiding in the accurate diagnosis of genetic abnormalities.
2. Research studies utilize the probe to investigate the role of chromosome 17 alterations in cancer progression and treatment response.
3. The probe is also used in treatment planning, helping clinicians tailor therapies based on the genetic profile of the tumor.
4. In clinical trials, the INFORM Chromosome 17 Probe is employed to monitor the effectiveness of new treatments targeting chromosomal abnormalities.
5. The probe's high specificity and sensitivity make it a valuable tool for quality control in molecular pathology laboratories.

The INFORM Chromosome 17 Probe is a versatile tool in clinical applications, from diagnostic testing to research and treatment planning. Its ability to detect chromosomal abnormalities with high specificity and sensitivity makes it indispensable in oncology. This probe not only aids in accurate diagnosis but also supports the development of personalized treatment strategies.

When purchasing the INFORM Chromosome 17 Probe, consider factors such as product specifications, types, budget, and intended use. This guide provides essential information to help you make an informed decision.

1. Product specifications: Ensure the probe meets your laboratory's requirements, including concentration, volume, and formulation.
2. Product types: Choose between different formulations or packaging options based on your specific needs and workflow.
3. Budget: Consider the cost-effectiveness of the probe, balancing quality and price to meet your laboratory's financial constraints.
4. Intended use: Select the probe that best fits your application, whether for diagnostic testing, research, or clinical trials.

Purchasing the INFORM Chromosome 17 Probe requires careful consideration of product specifications, types, budget, and intended use. This guide aims to simplify the decision-making process, ensuring you select the right probe for your laboratory's needs. By focusing on these key factors, you can make an informed choice that supports your diagnostic and research goals.

When using the INFORM Chromosome 17 Probe, it is essential to follow proper handling and storage procedures to ensure accurate results and maintain the probe's integrity.

1. Store the probe at the recommended temperature to prevent degradation and ensure stability.
2. Handle the probe with care, avoiding exposure to light and contaminants that could affect its performance.
3. Follow the manufacturer's protocol for hybridization and detection to achieve optimal results.
4. Use appropriate personal protective equipment (PPE) when handling the probe to ensure safety.
5. Regularly calibrate and maintain laboratory equipment to ensure accurate and consistent results.

Proper handling and storage of the INFORM Chromosome 17 Probe are crucial for maintaining its performance and ensuring accurate results. By following the recommended precautions, you can protect the probe's integrity and achieve reliable outcomes in your diagnostic and research applications. Always prioritize safety and adherence to protocols to maximize the probe's effectiveness.