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Type III Procollagen N-Terminal Peptide (PIIINP) Assay Kit (Latex-Enhanced Immunoturbidimetric Method)
The kit includes Reagent R1: Tris, NaCl, Proclin300; Reagent R2: PBS buffer, BSA, rabbit anti-human PIIINP antibody-coated latex particles, Proclin300. Optional components include Calibrator: containing Type III collagen, calf serum, Proclin300; Control: containing Type III collagen, phosphate buffer, Proclin300; and Diluent: containing phosphate buffer.
Product English Name:
Type III Procollagen N-Terminal Peptide (PIIINP) Assay Kit (Latex-Enhanced Immunoturbidimetric Method)
Alias:
PIIINP Kit,Collagen III Assay Kit
Intended Use:
This kit is designed for the quantitative determination of Type III Procollagen N-Terminal Peptide (PIIINP) in human serum, aiding in the assessment of fibrosis and tissue remodeling processes.
Product Introduction

The Type III Procollagen N-Terminal Peptide (PIIINP) Assay Kit is a sophisticated diagnostic tool used to measure the concentration of PIIINP in human serum. This peptide is a biomarker for collagen synthesis and degradation, making it crucial for monitoring conditions such as liver fibrosis, systemic sclerosis, and other fibrotic diseases. The kit employs a latex-enhanced immunoturbidimetric method, ensuring high sensitivity and specificity in detecting PIIINP levels.

1. The kit features a robust design with high-quality reagents, ensuring reliable and reproducible results. The latex-enhanced immunoturbidimetric method enhances the detection sensitivity, making it suitable for both clinical and research applications.
2. The composition includes Reagent R1 and R2, which are optimized for stability and performance. Optional components like Calibrator, Control, and Diluent provide flexibility in assay setup and validation, catering to diverse laboratory needs.
3. The primary use of the kit is to quantify PIIINP in serum, which is essential for diagnosing and monitoring fibrotic diseases. It is widely used in clinical laboratories, research institutions, and hospitals to assess collagen metabolism and tissue remodeling.

The PIIINP Assay Kit, also known as the Collagen III Assay Kit, is a vital tool in the field of fibrosis research and diagnostics. Its advanced methodology and comprehensive components make it a reliable choice for laboratories aiming to accurately measure PIIINP levels in human serum.

Main Features

The PIIINP Assay Kit offers high sensitivity and specificity in detecting Type III Procollagen N-Terminal Peptide, making it an essential tool for fibrosis research and diagnostics.

1. The kit utilizes a latex-enhanced immunoturbidimetric method, which significantly improves the detection sensitivity and accuracy of PIIINP levels in serum.
2. It includes high-quality reagents such as Tris, NaCl, and Proclin300 in Reagent R1, and PBS buffer, BSA, and antibody-coated latex particles in Reagent R2, ensuring stable and reliable performance.
3. Optional components like Calibrator, Control, and Diluent provide flexibility in assay setup, allowing laboratories to tailor the kit to their specific needs.
4. The kit is designed for ease of use, with clear instructions and protocols that facilitate quick and accurate results, even for less experienced users.
5. It is widely applicable in clinical settings, research institutions, and hospitals, providing valuable insights into collagen metabolism and tissue remodeling processes.

The PIIINP Assay Kit stands out for its high sensitivity, ease of use, and comprehensive components. It is an indispensable tool for researchers and clinicians focused on fibrosis and tissue remodeling, offering reliable and accurate results.

Clinical Applications

The PIIINP Assay Kit is extensively used in clinical settings to diagnose and monitor fibrotic diseases, providing critical insights into collagen metabolism and tissue health.

1. The kit is primarily used in the diagnosis of liver fibrosis, where elevated PIIINP levels indicate increased collagen synthesis and tissue remodeling.
2. It is also employed in the assessment of systemic sclerosis, a condition characterized by excessive collagen deposition in the skin and internal organs.
3. In research, the kit is used to study the mechanisms of fibrosis and the effects of therapeutic interventions on collagen metabolism.
4. The kit's high sensitivity makes it suitable for early detection of fibrotic changes, allowing for timely intervention and management of the disease.
5. It is also used in monitoring the progression of fibrotic diseases and evaluating the efficacy of antifibrotic treatments, providing valuable data for clinical decision-making.

The PIIINP Assay Kit is a cornerstone in the clinical management of fibrotic diseases. Its ability to accurately measure PIIINP levels provides clinicians and researchers with essential data for diagnosing, monitoring, and treating conditions related to collagen metabolism and tissue remodeling.

Purchasing Guide

When purchasing the PIIINP Assay Kit, consider factors such as product specifications, types, budget, and intended use to ensure it meets your laboratory's needs.

1. Product Parameters: Evaluate the kit's sensitivity, specificity, and detection range to ensure it aligns with your research or clinical requirements.
2. Product Types: Choose between standard and optional components like Calibrator, Control, and Diluent based on your laboratory's assay setup and validation needs.
3. Budget: Consider the cost-effectiveness of the kit, including the price per test and the availability of bulk purchase discounts.
4. Usage Scenarios: Assess the kit's compatibility with your laboratory's equipment and workflows, ensuring seamless integration and efficient use.

Selecting the right PIIINP Assay Kit involves careful consideration of product parameters, types, budget, and usage scenarios. By aligning these factors with your laboratory's needs, you can ensure optimal performance and value from the kit.

 Precautions

Proper handling and storage of the PIIINP Assay Kit are crucial to ensure accurate results and maintain the integrity of the reagents.

1. Storage: Store the kit at the recommended temperature to prevent degradation of the reagents and ensure long-term stability.
2. Handling: Follow the manufacturer's instructions for handling the reagents to avoid contamination and ensure accurate results.
3. Calibration: Regularly calibrate the assay using the provided Calibrator to maintain the accuracy and reliability of the measurements.
4. Quality Control: Use the Control samples to monitor the performance of the assay and detect any deviations from expected results.
5. Disposal: Dispose of used reagents and samples according to local regulations to ensure safety and environmental compliance.

Adhering to the recommended storage, handling, and disposal practices is essential for the optimal performance of the PIIINP Assay Kit. By following these precautions, you can ensure the accuracy and reliability of your results while maintaining a safe laboratory environment.

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