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HLA-DR Detection Reagent (Flow Cytometry-APC)
The HLA-DR Detection Reagent consists of a fluorescent APC-labeled monoclonal antibody specific to HLA-DR. Each 0.5 mL vial contains 25 μg of the antibody suspended in phosphate-buffered saline (PBS). This reagent is designed for precise detection and analysis of HLA-DR antigen expression in human cells.
Product English Name:
HLA-DR Detection Reagent (Flow Cytometry-APC)
Alias:
HLA-DR Antibody Reagent,APC-Labeled HLA-DR Reagent
Intended Use:
This product is used to identify the expression levels of HLA-DR antigens in human bone marrow and peripheral blood cells. It aids in the diagnosis of hematologic malignancies when combined with clinical symptoms and other diagnostic information.
Product Introduction

The HLA-DR Detection Reagent is a specialized tool for flow cytometry, designed to detect and quantify HLA-DR antigen expression on human cells. It is particularly useful in clinical and research settings for diagnosing blood-related diseases and understanding immune responses.

1. The reagent features a highly specific APC-labeled monoclonal antibody, ensuring accurate detection of HLA-DR antigens. Its fluorescence allows for easy visualization under flow cytometry.
2. The composition includes a stable formulation of the antibody in PBS, ensuring consistent performance and reliability in various laboratory conditions.
3. This reagent is primarily used in the diagnosis of hematologic malignancies, such as leukemia and lymphoma, by assessing HLA-DR expression levels in patient samples.

The HLA-DR Detection Reagent is a vital tool in modern diagnostics, offering precision and reliability. Its unique labeling and stable formulation make it indispensable for researchers and clinicians alike.

Main Features

The HLA-DR Detection Reagent excels in specificity, sensitivity, and ease of use, making it a preferred choice for flow cytometry applications.

1. High specificity: The APC-labeled antibody ensures accurate targeting of HLA-DR antigens without cross-reactivity.
2. Sensitivity: The reagent can detect low levels of HLA-DR expression, crucial for early disease detection.
3. Stability: The PBS-based formulation maintains antibody integrity over extended periods.
4. Compatibility: Designed for use with standard flow cytometry equipment, ensuring seamless integration into existing workflows.
5. Diagnostic utility: Plays a key role in identifying hematologic malignancies and monitoring disease progression.

With its advanced features, the HLA-DR Detection Reagent stands out as a reliable and efficient solution for flow cytometry-based diagnostics.

Clinical Applications

This reagent is widely used in clinical settings for diagnosing and monitoring blood-related diseases, particularly hematologic malignancies.

1. Diagnosis of leukemia: Helps identify abnormal HLA-DR expression in leukemic cells.
2. Lymphoma detection: Assists in distinguishing lymphoma subtypes based on HLA-DR levels.
3. Immune monitoring: Used to assess immune cell activity in patients undergoing immunotherapy.
4. Research applications: Supports studies on HLA-DR's role in immune responses and disease mechanisms.
5. Prognostic tool: Provides insights into disease progression and treatment efficacy.

The HLA-DR Detection Reagent is a versatile tool in clinical diagnostics, offering valuable insights into disease mechanisms and patient outcomes.

Purchasing Guide

When purchasing the HLA-DR Detection Reagent, consider factors such as product specifications, intended use, and budget to ensure optimal results.

1. Product parameters: Verify the antibody concentration, labeling efficiency, and compatibility with your flow cytometry system.
2. Product types: Choose between bulk or single-use formats based on your laboratory's needs.
3. Budget considerations: Evaluate cost-effectiveness while ensuring high-quality performance.
4. Usage scenarios: Ensure the reagent aligns with your diagnostic or research objectives.

Selecting the right HLA-DR Detection Reagent requires careful consideration of technical and financial factors to meet your specific needs.

 Precautions

Proper handling and storage of the HLA-DR Detection Reagent are essential to maintain its efficacy and ensure accurate results.

1. Storage: Keep the reagent at 2-8°C and protect it from light to prevent degradation.
2. Handling: Use sterile techniques to avoid contamination during sample preparation.
3. Usage: Follow the manufacturer's instructions for optimal antibody dilution and incubation times.
4. Disposal: Dispose of used reagents according to local biohazard waste regulations.
5. Quality control: Regularly validate the reagent's performance using control samples.

Adhering to these precautions ensures the HLA-DR Detection Reagent remains effective and reliable, supporting accurate diagnostic outcomes.

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