The INFORM HER2 Dual ISH DNA Probe Cocktail is a sophisticated diagnostic tool designed to detect HER2 gene amplification in cancer tissues. Utilizing in situ hybridization, this product offers a reliable method for identifying genetic alterations that are crucial for cancer diagnosis and treatment planning.

1. The HER2 Dual ISH Probe is characterized by its high specificity and sensitivity, ensuring accurate detection of HER2 gene amplification. This feature is vital for determining the appropriate therapeutic approach for patients with breast and gastric cancers.
2. The product's composition includes a HER2 probe labeled with DNP and a Chromosome 17 probe labeled with Digoxigenin, both prepared in a formamide buffer with human placental DNA. This unique formulation enhances the stability and accuracy of the hybridization process.
3. The primary use of this product is in the qualitative detection of HER2 gene amplification in formalin-fixed, paraffin-embedded tissue samples. It is particularly useful in diagnosing and managing breast and gastric cancers, where HER2 status is a critical factor in treatment decisions.

The INFORM HER2 Dual ISH DNA Probe Cocktail, also known as the HER2 Dual ISH Probe, is an essential tool in modern oncology. Its precise detection capabilities and robust composition make it indispensable for diagnosing and managing HER2-positive cancers.

The INFORM HER2 Dual ISH DNA Probe Cocktail offers high specificity and sensitivity in detecting HER2 gene amplification, making it a critical tool in cancer diagnostics.

1. The product provides high specificity in detecting HER2 gene amplification, reducing the risk of false positives and ensuring accurate diagnosis.
2. Its sensitivity allows for the detection of low levels of HER2 amplification, which is crucial for early cancer detection and treatment planning.
3. The dual-probe system, combining HER2 and Chromosome 17 probes, enhances the accuracy of the hybridization process, providing reliable results.
4. The use of formamide buffer and human placental DNA in the probe preparation ensures stability and consistency in performance.
5. The product is designed for use with formalin-fixed, paraffin-embedded tissue samples, making it versatile and applicable in various clinical settings.

The INFORM HER2 Dual ISH DNA Probe Cocktail stands out for its precision and reliability in detecting HER2 gene amplification. Its advanced features make it a trusted choice for oncologists and pathologists.

The INFORM HER2 Dual ISH DNA Probe Cocktail is widely used in clinical settings to diagnose and manage HER2-positive breast and gastric cancers.

1. In breast cancer diagnostics, the product is used to determine HER2 status, which is crucial for selecting targeted therapies such as trastuzumab.
2. For gastric cancer, the probe helps identify HER2 amplification, guiding the use of HER2-targeted treatments and improving patient outcomes.
3. The product is also used in research settings to study HER2 gene amplification and its role in cancer progression and treatment resistance.
4. Clinical trials often utilize this probe to assess the efficacy of new HER2-targeted therapies, providing valuable data for drug development.
5. Pathologists rely on the INFORM HER2 Dual ISH DNA Probe Cocktail for accurate and reproducible results, ensuring high standards in cancer diagnostics.

The INFORM HER2 Dual ISH DNA Probe Cocktail is a cornerstone in the clinical management of HER2-positive cancers. Its applications extend from routine diagnostics to cutting-edge research, making it an invaluable tool in oncology.

When purchasing the INFORM HER2 Dual ISH DNA Probe Cocktail, consider product specifications, types, budget, and intended use to ensure optimal performance and cost-effectiveness.

1. Product parameters such as sensitivity, specificity, and stability should be evaluated to ensure the probe meets diagnostic requirements.
2. Different product types may be available, so choose the one that best fits your laboratory's needs and workflow.
3. Budget considerations are important, but should not compromise the quality and reliability of the product.
4. Consider the intended use, whether for routine diagnostics, research, or clinical trials, to select the most appropriate probe.

Purchasing the INFORM HER2 Dual ISH DNA Probe Cocktail requires careful consideration of various factors to ensure it meets your diagnostic and research needs effectively.

Proper handling and usage of the INFORM HER2 Dual ISH DNA Probe Cocktail are essential to ensure accurate results and maintain product integrity.

1. Always follow the manufacturer's instructions for storage and handling to prevent degradation of the probes.
2. Ensure that the tissue samples are properly fixed and embedded to avoid artifacts that could affect the hybridization process.
3. Use appropriate controls to validate the results and ensure the accuracy of the HER2 status determination.
4. Regularly calibrate and maintain the equipment used in the hybridization process to ensure consistent performance.
5. Dispose of any hazardous materials according to local regulations to maintain a safe laboratory environment.

Adhering to the recommended precautions when using the INFORM HER2 Dual ISH DNA Probe Cocktail is crucial for obtaining reliable and accurate diagnostic results. Proper handling and maintenance ensure the product's effectiveness and longevity.