The HER2/17 Chromosome DNA Dual Probe INFORM HER2 Dual ISH DNA Probe Cocktail is a sophisticated diagnostic tool designed for the precise detection of HER2 gene amplification. This product is essential in the field of oncology, particularly for breast cancer diagnostics, where HER2 status is a critical factor in treatment decisions. The dual probe system allows for simultaneous detection of HER2 and chromosome 17, providing a comprehensive analysis of gene amplification.

1. The HER2/17 Chromosome DNA Dual Probe is characterized by its high specificity and sensitivity. The DNP-labeled HER2 probe and DIG-labeled chromosome 17 probe are designed to bind specifically to their respective targets, ensuring accurate detection of gene amplification.
2. The product is composed of a hybridization buffer that includes human placental blocking DNA, which minimizes non-specific binding. The formulation ensures optimal conditions for probe hybridization, enhancing the reliability of the results.
3. This probe cocktail is used in the quantitative assessment of HER2 gene amplification in tissue samples. It is particularly valuable in clinical settings where determining HER2 status is crucial for patient management and treatment planning.

The HER2/17 Chromosome DNA Dual Probe INFORM HER2 Dual ISH DNA Probe Cocktail is a vital tool in molecular diagnostics, offering precise detection of HER2 gene amplification. Its dual probe system and optimized formulation make it an indispensable resource for pathologists and oncologists in managing breast cancer and other HER2-related conditions.

The HER2/17 Chromosome DNA Dual Probe offers high specificity and sensitivity in detecting HER2 gene amplification, making it a critical tool in cancer diagnostics.

1. The DNP-labeled HER2 probe ensures high specificity in binding to HER2 gene sequences, reducing the risk of false positives.
2. The DIG-labeled chromosome 17 probe provides a reference for gene copy number, allowing for accurate quantification of HER2 amplification.
3. The hybridization buffer, formulated with human placental blocking DNA, minimizes non-specific binding, enhancing the accuracy of the results.
4. The product is designed for use in automated staining platforms, streamlining the diagnostic process and reducing manual handling errors.
5. The dual probe system allows for simultaneous detection of HER2 and chromosome 17, providing a comprehensive analysis in a single assay.

The HER2/17 Chromosome DNA Dual Probe is a highly reliable and efficient tool for detecting HER2 gene amplification. Its advanced features, including high specificity, accurate quantification, and streamlined automation, make it an essential component in modern cancer diagnostics.

The HER2/17 Chromosome DNA Dual Probe is widely used in clinical settings for the assessment of HER2 status in breast cancer and other malignancies.

1. In breast cancer diagnostics, the probe is used to determine HER2 gene amplification, which is crucial for selecting targeted therapies such as trastuzumab.
2. The probe is also applied in the diagnosis of gastric cancer, where HER2 status influences treatment decisions.
3. In research settings, the probe is used to study the molecular mechanisms of HER2 amplification and its role in cancer progression.
4. The product is utilized in clinical trials to evaluate the efficacy of new HER2-targeted therapies.
5. Pathologists use the probe in routine diagnostic workflows to provide accurate and timely HER2 status reports, aiding in patient management.

The HER2/17 Chromosome DNA Dual Probe plays a pivotal role in clinical diagnostics and research, particularly in the management of HER2-positive cancers. Its application in determining HER2 status is essential for guiding treatment strategies and improving patient outcomes.

When purchasing the HER2/17 Chromosome DNA Dual Probe, consider product specifications, types, budget, and intended use to ensure optimal selection.

1. Product parameters such as probe concentration, buffer composition, and compatibility with staining platforms should be evaluated to match laboratory requirements.
2. Different product types, including manual and automated versions, are available. Choose based on the laboratory's workflow and throughput needs.
3. Budget considerations should include not only the initial purchase cost but also long-term expenses related to storage, handling, and potential reorders.
4. The intended use, whether for routine diagnostics, research, or clinical trials, will influence the choice of product features and specifications.

Selecting the right HER2/17 Chromosome DNA Dual Probe involves careful consideration of product specifications, types, budget, and intended use. A well-informed purchase ensures that the product meets the laboratory's needs and enhances diagnostic accuracy.

Proper handling and storage of the HER2/17 Chromosome DNA Dual Probe are essential to maintain its efficacy and ensure accurate results.

1. Store the probe at the recommended temperature to prevent degradation of the probes and buffer components.
2. Handle the product with care to avoid contamination, which can lead to inaccurate results.
3. Follow the manufacturer's instructions for use, including proper dilution and incubation times, to ensure optimal performance.
4. Dispose of used reagents and materials according to local regulations to prevent environmental contamination.
5. Regularly calibrate and maintain equipment used with the probe to ensure consistent and reliable results.

Adhering to proper handling, storage, and usage guidelines for the HER2/17 Chromosome DNA Dual Probe is crucial for maintaining its performance and ensuring accurate diagnostic results. Careful attention to these precautions will enhance the reliability of the assay and contribute to better patient outcomes.