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HER-2 Antibody Reagent (Immunohistochemistry)
The HER-2 Antibody Reagent is composed of a rabbit anti-human HER-2/neu monoclonal antibody, specifically designed for immunohistochemical applications. This reagent is derived from rabbit cell culture supernatant and is identified by the clone number MXR001. It is formulated to ensure high specificity and sensitivity in detecting HER-2 protein expression in human tissues.
Product English Name:
HER-2 Antibody Reagent (Immunohistochemistry)
Alias:
HER-2 IHC Reagent,HER-2/neu Antibody
Intended Use:
This antibody reagent is primarily used for the qualitative detection of HER-2 protein in formalin-fixed, paraffin-embedded human breast tissue sections. It is a critical tool in the diagnosis and classification of breast cancer, helping to determine the HER-2 status of tumors, which is essential for guiding targeted therapy decisions.
Product Introduction

The HER-2 Antibody Reagent is a specialized diagnostic tool used in immunohistochemistry to detect HER-2 protein expression in breast cancer tissues. HER-2 is a protein that can promote the growth of cancer cells, and its overexpression is associated with aggressive forms of breast cancer. This reagent is designed to provide accurate and reliable results, aiding in the diagnosis and treatment planning for patients with breast cancer.

1. The HER-2 Antibody Reagent is characterized by its high specificity and sensitivity, ensuring precise detection of HER-2 protein in tissue samples. It is optimized for use with formalin-fixed, paraffin-embedded tissues, making it suitable for routine clinical pathology workflows.
2. The reagent is composed of a rabbit anti-human HER-2/neu monoclonal antibody, derived from rabbit cell culture supernatant. The antibody is of the IgG class and is identified by the clone number MXR001, ensuring consistency and reliability in its performance.
3. This reagent is used for the qualitative detection of HER-2 protein in human breast tissue sections. It plays a crucial role in determining the HER-2 status of breast cancer tumors, which is essential for guiding targeted therapy and improving patient outcomes.

The HER-2 Antibody Reagent, also known as HER-2 IHC Reagent, is a vital tool in the diagnosis of breast cancer. Its high specificity and sensitivity make it an indispensable component in clinical pathology labs, helping to determine the HER-2 status of tumors and guide treatment decisions.

Main Features

The HER-2 Antibody Reagent offers high specificity and sensitivity for detecting HER-2 protein in breast cancer tissues. It is optimized for use with formalin-fixed, paraffin-embedded tissues, ensuring reliable results in clinical settings.

1. High specificity: The reagent is designed to specifically bind to HER-2 protein, minimizing cross-reactivity with other proteins and ensuring accurate detection.
2. Sensitivity: It is highly sensitive, capable of detecting low levels of HER-2 protein expression, which is crucial for identifying HER-2 positive breast cancers.
3. Compatibility: The reagent is compatible with formalin-fixed, paraffin-embedded tissues, making it suitable for routine clinical use.
4. Consistency: The use of a monoclonal antibody ensures batch-to-batch consistency, providing reliable results across different laboratories.
5. Diagnostic utility: The reagent is essential for determining the HER-2 status of breast cancer tumors, which is critical for guiding targeted therapy and improving patient outcomes.

The HER-2 Antibody Reagent is a highly specific and sensitive tool for detecting HER-2 protein in breast cancer tissues. Its compatibility with routine clinical workflows and consistent performance make it an invaluable asset in the diagnosis and treatment of breast cancer.

Clinical Applications

The HER-2 Antibody Reagent is widely used in clinical pathology for the detection of HER-2 protein in breast cancer tissues. It is essential for determining the HER-2 status of tumors, which guides targeted therapy decisions.

1. Diagnosis: The reagent is used to diagnose HER-2 positive breast cancer, which is characterized by the overexpression of HER-2 protein.
2. Prognosis: HER-2 status is a prognostic marker, helping to predict the aggressiveness of the cancer and the likelihood of recurrence.
3. Treatment planning: The detection of HER-2 protein is crucial for selecting appropriate targeted therapies, such as trastuzumab, which specifically target HER-2 positive cancers.
4. Research: The reagent is also used in research settings to study the role of HER-2 in cancer biology and to develop new therapeutic strategies.
5. Quality control: In clinical laboratories, the reagent is used for quality control purposes to ensure the accuracy and reliability of HER-2 testing.

The HER-2 Antibody Reagent is a cornerstone in the clinical management of breast cancer. Its ability to accurately detect HER-2 protein expression is essential for diagnosis, prognosis, and treatment planning, making it a critical tool in modern oncology.

Purchasing Guide

When purchasing the HER-2 Antibody Reagent, it is important to consider product specifications, types, budget, and intended use to ensure it meets the needs of your laboratory.

1. Product parameters: Ensure the reagent has the necessary specificity, sensitivity, and compatibility with your laboratory's workflow.
2. Product types: Choose between different formats, such as ready-to-use or concentrated versions, based on your laboratory's requirements.
3. Budget: Consider the cost-effectiveness of the reagent, including the price per test and the potential for bulk discounts.
4. Usage scenarios: Evaluate the reagent's suitability for your specific applications, such as routine diagnostics or research purposes.

Selecting the right HER-2 Antibody Reagent involves careful consideration of product specifications, types, budget, and intended use. By taking these factors into account, you can ensure that the reagent meets your laboratory's needs and provides reliable results.

 Precautions

Proper handling and storage of the HER-2 Antibody Reagent are essential to maintain its performance and ensure accurate results.

1. Storage: Store the reagent at the recommended temperature to preserve its stability and activity.
2. Handling: Follow proper laboratory protocols to avoid contamination and ensure the integrity of the reagent.
3. Usage: Use the reagent within its expiration date and follow the manufacturer's instructions for optimal performance.
4. Disposal: Dispose of used reagents and materials according to local regulations and laboratory safety guidelines.
5. Training: Ensure that laboratory personnel are properly trained in the use of the reagent and understand the importance of following protocols.

The HER-2 Antibody Reagent requires careful handling and storage to maintain its performance. By following proper protocols and ensuring that laboratory personnel are well-trained, you can achieve accurate and reliable results in HER-2 testing.

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