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17-Ketosteroid Assay Kit (Latex Enhanced Immunoturbidimetric Method)
The 17-Ketosteroid Assay Kit is composed of two main reagents: R1 and R2. R1 contains Tris(hydroxymethyl)aminomethane (Trizma Base), polyethylene glycol 20000 (PEG20000), 17-ketosteroid conjugate, and a preservative (proclin300). R2 consists of latex particles coated with rabbit anti-human 17-ketosteroid polyclonal antibodies, disodium hydrogen phosphate (Na2HPO4), potassium dihydrogen phosphate (KH2PO4), and a preservative (proclin300). The final pH of both reagents is adjusted to 8.0.
Product English Name:
17-Ketosteroid Assay Kit (Latex Enhanced Immunoturbidimetric Method)
Alias:
17-KS Test Kit,17-Ketosteroid Diagnostic Kit
Intended Use:
This kit is designed for the quantitative in vitro determination of 17-ketosteroids in human urine. It is clinically used as an auxiliary diagnostic tool for adrenal cortex diseases, helping to assess the functional status of the adrenal glands.
Product Introduction

The 17-Ketosteroid Assay Kit is a sophisticated diagnostic tool used in clinical laboratories to measure the levels of 17-ketosteroids in human urine. These steroids are metabolites of adrenal and gonadal hormones, and their levels can provide critical insights into adrenal gland function. The kit employs a latex-enhanced immunoturbidimetric method, which ensures high sensitivity and specificity in detecting 17-ketosteroids. It is widely used in endocrinology to aid in the diagnosis of adrenal cortex disorders.

1. The kit features a latex-enhanced immunoturbidimetric method, which enhances the sensitivity and specificity of the assay. This method allows for the precise detection of 17-ketosteroids even at low concentrations, making it highly reliable for clinical diagnostics.
2. The composition of the kit includes two main reagents: R1 and R2. R1 contains a buffer system, a stabilizer, and a 17-ketosteroid conjugate, while R2 consists of latex particles coated with specific antibodies. The combination of these components ensures accurate and reproducible results.
3. The primary use of the kit is to quantify 17-ketosteroids in human urine, which is crucial for diagnosing adrenal cortex diseases. By measuring these metabolites, clinicians can assess adrenal gland function and identify potential endocrine disorders.

The 17-Ketosteroid Assay Kit, also known as the 17-KS Test Kit, is a vital tool in clinical diagnostics. Its advanced immunoturbidimetric method and well-designed composition make it a reliable choice for measuring 17-ketosteroids in urine. This kit plays a crucial role in the diagnosis and management of adrenal cortex diseases, providing clinicians with valuable insights into adrenal gland function.

Main Features

The 17-Ketosteroid Assay Kit offers high sensitivity and specificity in detecting 17-ketosteroids, making it an essential tool for clinical diagnostics. Its latex-enhanced immunoturbidimetric method ensures accurate and reproducible results.

1. The kit utilizes a latex-enhanced immunoturbidimetric method, which significantly improves the detection sensitivity of 17-ketosteroids. This method is particularly effective in identifying low concentrations of these metabolites in urine samples.
2. The composition of the kit includes two reagents: R1 and R2. R1 contains a buffer system and a stabilizer, while R2 consists of latex particles coated with specific antibodies. This combination ensures the stability and accuracy of the assay.
3. The kit is designed for the quantitative measurement of 17-ketosteroids in human urine. This measurement is crucial for diagnosing adrenal cortex diseases and assessing adrenal gland function.
4. The assay is highly reproducible, with consistent results across different batches and laboratories. This reliability makes it a preferred choice for clinical diagnostics.
5. The kit is easy to use, with a straightforward protocol that minimizes the risk of user error. This simplicity ensures that even less experienced technicians can obtain accurate results.

The 17-Ketosteroid Assay Kit stands out for its high sensitivity, specificity, and reproducibility. Its latex-enhanced immunoturbidimetric method and well-designed composition make it an indispensable tool for clinical diagnostics, particularly in the assessment of adrenal gland function.

Clinical Applications

The 17-Ketosteroid Assay Kit is primarily used in clinical settings to diagnose adrenal cortex diseases. It provides quantitative measurements of 17-ketosteroids in urine, which are essential for assessing adrenal gland function.

1. The kit is used in endocrinology to diagnose adrenal cortex disorders such as Cushing's syndrome and Addison's disease. By measuring 17-ketosteroid levels, clinicians can assess the functional status of the adrenal glands.
2. It is also employed in the evaluation of gonadal function, as 17-ketosteroids are metabolites of both adrenal and gonadal hormones. This dual role makes the kit valuable in comprehensive endocrine assessments.
3. The kit is used in research settings to study the effects of various treatments on adrenal gland function. Its high sensitivity and specificity make it a reliable tool for such studies.
4. In clinical laboratories, the kit is used for routine screening of patients with suspected adrenal cortex disorders. Its ease of use and reproducibility make it a preferred choice for high-throughput testing.
5. The kit is also used in the monitoring of patients undergoing treatment for adrenal cortex diseases. Regular measurements of 17-ketosteroids help clinicians adjust treatment plans and assess patient progress.

The 17-Ketosteroid Assay Kit is a versatile tool in clinical diagnostics, particularly in the field of endocrinology. Its ability to provide accurate and reproducible measurements of 17-ketosteroids makes it essential for diagnosing and managing adrenal cortex diseases.

Purchasing Guide

When purchasing the 17-Ketosteroid Assay Kit, it is important to consider factors such as product specifications, types, budget, and intended use. This guide provides essential information to help you make an informed decision.

1. Product specifications: Ensure that the kit meets your laboratory's requirements in terms of sensitivity, specificity, and reproducibility. Check the composition and storage conditions to ensure compatibility with your lab's protocols.
2. Product types: The kit is available in different formats, including single-use and bulk packages. Choose the format that best suits your laboratory's needs and testing volume.
3. Budget: Consider the cost of the kit, including any additional reagents or equipment that may be required. Compare prices from different suppliers to find the best value for your budget.
4. Intended use: Determine the primary application of the kit in your laboratory. Whether for routine screening, research, or patient monitoring, ensure that the kit's features align with your intended use.

Purchasing the 17-Ketosteroid Assay Kit requires careful consideration of product specifications, types, budget, and intended use. By evaluating these factors, you can select the kit that best meets your laboratory's needs and ensures accurate and reliable results.

 Precautions

When using the 17-Ketosteroid Assay Kit, it is important to follow proper handling and storage procedures to ensure accurate results and user safety. This section outlines key precautions to consider.

1. Storage: Store the kit at the recommended temperature to maintain the stability of the reagents. Avoid exposure to extreme temperatures or direct sunlight.
2. Handling: Use appropriate personal protective equipment (PPE) when handling the reagents. Avoid contact with skin and eyes, and wash hands thoroughly after use.
3. Sample preparation: Ensure that urine samples are collected and prepared according to the kit's instructions. Improper sample handling can lead to inaccurate results.
4. Calibration: Regularly calibrate the assay using the provided standards to ensure accurate and reproducible results. Follow the calibration protocol carefully.
5. Disposal: Dispose of used reagents and samples in accordance with local regulations. Use designated waste containers to prevent environmental contamination.

Proper handling, storage, and disposal of the 17-Ketosteroid Assay Kit are essential for obtaining accurate results and ensuring user safety. By following the recommended precautions, you can minimize the risk of errors and maintain the integrity of your laboratory's diagnostic processes.

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