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CYP2C19 Gene Polymorphism Detection Kit (Fluorescent PCR Method)
The kit consists of a 6-well PCR reaction strip (ZC) and a positive control (ZC). Each well in the 6-well PCR reaction strip corresponds to specific detection types: CYP2C19*2 wild-type, CYP2C19*2 mutant, CYP2C19*3 wild-type, CYP2C19*3 mutant, CYP2C19*17 wild-type, and CYP2C19*17 mutant. The fluorescent probe signals include FAM and internal control JOE signals, which ensure quality control for the kit, DNA quality, and operational procedures.
Product English Name:
CYP2C19 Gene Polymorphism Detection Kit (Fluorescent PCR Method)
Alias:
CYP2C19 Genotyping Kit,PCR-Based CYP2C19 Detection Kit
Intended Use:
This product is designed for the qualitative detection of CYP2C19 gene alleles CYP2C19*2 (G>A), CYP2C19*3 (G>A), and CYP2C19*17 (C>T) in genomic DNA extracted from human peripheral blood. It is intended for research use and has not been clinically validated for specific drug interactions, focusing solely on the detection performance of target gene mutations.
Product Introduction

The CYP2C19 Gene Polymorphism Detection Kit is a cutting-edge tool designed for the precise identification of genetic variations in the CYP2C19 gene. Utilizing fluorescent PCR technology, this kit offers high sensitivity and specificity, making it an essential resource for genetic research and personalized medicine. Its robust design ensures reliable results, aiding in the understanding of genetic predispositions and drug metabolism.

1. The kit features advanced fluorescent PCR technology, ensuring high accuracy and reproducibility in detecting CYP2C19 gene polymorphisms. Its design minimizes cross-contamination and enhances detection efficiency.
2. Structurally, the kit includes a 6-well PCR reaction strip and a positive control. Each well is pre-configured to detect specific CYP2C19 alleles, with FAM and JOE signals providing dual-channel detection for enhanced reliability.
3. Primarily used in research settings, this kit aids in identifying genetic variations that influence drug metabolism. It is particularly valuable in pharmacogenomics, helping to tailor drug therapies based on individual genetic profiles.

The CYP2C19 Gene Polymorphism Detection Kit, also known as the CYP2C19 Genotyping Kit, is a sophisticated tool for genetic analysis. Its dual-channel detection system and pre-configured reaction strips make it a reliable choice for researchers exploring the complexities of drug metabolism and genetic predispositions.

Main Features

The CYP2C19 Gene Polymorphism Detection Kit offers high sensitivity, specificity, and reproducibility in detecting genetic variations. Its dual-channel fluorescent detection system ensures accurate and reliable results.

1. High Sensitivity: The kit can detect low-frequency genetic mutations with high precision, making it suitable for research requiring detailed genetic analysis.
2. Dual-Channel Detection: Utilizing FAM and JOE signals, the kit provides a robust internal control mechanism, ensuring the reliability of results.
3. Pre-Configured Strips: The 6-well PCR reaction strips are pre-configured for specific CYP2C19 alleles, simplifying the detection process and reducing setup time.
4. Quality Control: The inclusion of a positive control and internal JOE signal ensures the integrity of the kit, DNA quality, and operational procedures.
5. Research Applications: Ideal for pharmacogenomics and personalized medicine, the kit aids in understanding genetic variations that influence drug metabolism.

The CYP2C19 Gene Polymorphism Detection Kit stands out for its high sensitivity, dual-channel detection, and pre-configured design. These features make it an indispensable tool for researchers delving into the genetic factors affecting drug metabolism and personalized medicine.

Clinical Applications

The CYP2C19 Gene Polymorphism Detection Kit is primarily used in research settings to study genetic variations that influence drug metabolism. It aids in pharmacogenomics and personalized medicine.

1. Pharmacogenomics Research: The kit is widely used in studies exploring the relationship between genetic variations and drug response, helping to tailor therapies based on individual genetic profiles.
2. Drug Metabolism Studies: Researchers use the kit to investigate how CYP2C19 gene polymorphisms affect the metabolism of various drugs, providing insights into drug efficacy and safety.
3. Clinical Trials: The kit is employed in clinical trials to identify genetic markers that may influence drug response, aiding in the development of personalized treatment plans.
4. Genetic Counseling: The kit supports genetic counseling by providing detailed information on CYP2C19 gene polymorphisms, helping patients understand their genetic predispositions.
5. Academic Research: The kit is a valuable tool in academic research, facilitating studies on genetic variations and their impact on health and disease.

The CYP2C19 Gene Polymorphism Detection Kit is a versatile tool in pharmacogenomics and personalized medicine. Its applications range from drug metabolism studies to clinical trials, making it an essential resource for researchers and clinicians alike.

Purchasing Guide

When purchasing the CYP2C19 Gene Polymorphism Detection Kit, consider product specifications, types, budget, and intended use to ensure it meets your research needs.

1. Product Specifications: Evaluate the kit's sensitivity, specificity, and detection capabilities to ensure it aligns with your research requirements.
2. Product Types: Choose between different kit configurations based on the number of samples and specific CYP2C19 alleles you intend to analyze.
3. Budget Considerations: Assess the cost-effectiveness of the kit, considering its features and the scale of your research project.
4. Usage Scenarios: Determine the kit's suitability for your research environment, ensuring it meets safety and operational standards.

Selecting the right CYP2C19 Gene Polymorphism Detection Kit involves careful consideration of product specifications, types, budget, and usage scenarios. Ensuring these factors align with your research needs will maximize the kit's utility and effectiveness.

 Precautions

Proper handling, storage, and usage of the CYP2C19 Gene Polymorphism Detection Kit are crucial to ensure accurate results and maintain product integrity.

1. Storage Conditions: Store the kit at the recommended temperature to preserve the stability of reagents and ensure reliable performance.
2. Handling Procedures: Follow proper handling protocols to avoid contamination and ensure the integrity of samples and reagents.
3. Usage Guidelines: Adhere to the manufacturer's instructions for optimal performance, including proper setup and operation of the PCR system.
4. Safety Measures: Implement safety precautions to protect users from potential hazards associated with handling biological samples and reagents.
5. Quality Control: Regularly perform quality control checks to verify the kit's performance and ensure consistent, accurate results.

Ensuring the proper storage, handling, and usage of the CYP2C19 Gene Polymorphism Detection Kit is essential for maintaining its performance and reliability. Adhering to safety and quality control measures will help achieve accurate and consistent results in your research.

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